| Clotrimazole and enilconazole distribution within the frontal sinuses and nasal cavity of nine dogs with sinonasal aspergillosis. | |
| | |
MedLine Citation:
|
PMID: 22300493 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
Objectives: Multiple topical treatments are often required for clinical cure of mycotic rhinosinusitis in dogs. The objective of this study was to describe the distribution and retention of enilconazole and clotrimazole solutions using a temporary trephination protocol. Methods: Nine client-owned dogs diagnosed with mycotic rhinosinusitis between March 2008 and December 2009 were prospectively enrolled and were sequentially allocated to receive treatment with either clotrimazole (1% in polyethylene glycol) or enilconazole (10% solution), after imaging and rhinoscopic assessment. Both frontal sinuses were trephined, debrided and flushed with saline. Infusion was administered via frontal sinuses with dogs in sternal recumbency and computed tomography (CT) performed 5 minutes after completion. Distribution was scored 1 to 4 at the canine tooth, premolar 4, cribriform plate and frontal sinus on both sides, for a maximum score of 32. Results: Distribution of antifungal agents to all regions of the nasal cavity and frontal sinuses was achievable, but varied considerably. Retention was poor in 10 of 18 regions assessed. Clinical Significance: Distribution of antifungal agents within the frontal sinuses is achievable using temporary trephination; however, distribution is variable and retention is often poor. |
| | |
Authors:
|
M Sharman; Z Lenard; G Hosgood; C Mansfield |
Related Documents
:
|
10336193 - Use of ct in detection of internal damage and repair and determination of authenticity ... 22145473 - Seventeen-year-old adolescent with pituitary abscess. 21361133 - In vivo photodynamic therapy and magnetic resonance imaging of cancer by tspp-coated fe... |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2012-2-2 |
Journal Detail:
|
Title: The Journal of small animal practice Volume: - ISSN: 1748-5827 ISO Abbreviation: - Publication Date: 2012 Feb |
Date Detail:
|
Created Date: 2012-2-3 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0165053 Medline TA: J Small Anim Pract Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
© 2012 British Small Animal Veterinary Association. |
Affiliation:
|
Department of Veterinary Clinical Sciences, Murdoch University, South St, Murdoch, Western Australia 6150, Australia Veterinary Imaging Centre, Perth Veterinary Specialists, 305 Selby St, Osborne Park, Western Australia 6017, Australia. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Association of platelet counts decline and mortality in severely burnt patients.
Next Document: Banff 2011 Meeting Report: New Concepts in Antibody-Mediated Rejection.