Document Detail

Closure of the patent ductus arteriosus with the new duct occluder II additional sizes device.
MedLine Citation:
PMID:  22422478     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: The objective of this study was to evaluate the technical feasibility, safety, and efficacy of the new device Amplatzer duct occluder II additional sizes (ADO II AS) for closure of patent ductus arteriosus (PDA).
BACKGROUND: Transcatheter device closure is the standard care for PDA. Currently available technology is not designed for closure of small PDA in young children.
METHODS: From April to July 2011, seven children (five females, median age 1.5 years, median weight 11.4 kg) underwent PDA closure with the ADO II AS. Six had isolated PDA, one had PDA associated with preductal coarctation. We evaluated early and short-term results.
RESULTS: All but one PDA was closed via an antegrade approach. Mean fluoroscopy and procedural times were 8.0 ± 3.9 and 49.8 ± 27.9 min, respectively. No complications occurred. Immediate trivial residual shunt was present in one patient. In all devices, the retention disks laid flat against the walls of the pulmonary artery and aorta, without protrusion into the vessel lumen. The echocardiography performed after 24 hr did not show any residual shunt. At a median follow-up of 2 months, the PDAs were completely occluded without obstruction of the pulmonary arteries or aorta.
CONCLUSIONS: The new device ADO II AS was safely deployed with complete resolution of the PDA shunt. The lower profile and symmetry of this device allows for venous or arterial approach and smaller delivery catheter size. The ADO II AS might be a preferable alternative for closure of small-moderate PDAs.
Gabriella Agnoletti; D Marini; A M Villar; R Bordese; F Gabbarini
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Publication Detail:
Type:  Evaluation Studies; Journal Article     Date:  2012-03-15
Journal Detail:
Title:  Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions     Volume:  79     ISSN:  1522-726X     ISO Abbreviation:  Catheter Cardiovasc Interv     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-06-07     Completed Date:  2012-10-10     Revised Date:  2014-07-31    
Medline Journal Info:
Nlm Unique ID:  100884139     Medline TA:  Catheter Cardiovasc Interv     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1169-74     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Wiley Periodicals, Inc.
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MeSH Terms
Cardiac Catheterization / adverse effects,  instrumentation*
Child, Preschool
Ductus Arteriosus, Patent / diagnosis,  therapy*
Echocardiography, Doppler, Color
Feasibility Studies
Prosthesis Design
Radiography, Interventional
Time Factors
Treatment Outcome
Comment In:
Catheter Cardiovasc Interv. 2012 Jun 1;79(7):1175   [PMID:  22674765 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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