| Closure of a large patent ductus arteriosus in children and adults with pulmonary hypertension. | |
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MedLine Citation:
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PMID: 20118039 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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INTRODUCTION: Surgical closure of a patent ductus arteriosus (PDA) in cases with pulmonary hypertension, a short and wide PDA, and/or calcification of the wall of the vessel can be a hazardous procedure. The use of extracorporeal circulation provides the necessary safety for effective closure. METHODS: Four patients (one male), aged 7, 22, 54 and 60 years old, underwent PDA closure. All had pulmonary hypertension (pulmonary artery pressure, PAP 55-85 mmHg, PAP-to-systemic pressure ratio 0.6-0.8) and a wide, short PDA (diameter 9-12 mm) with a calcified wall in 2 cases. The surgical technique involved transpulmonary PDA closure with a synthetic patch under extracorporeal circulation and mild hypothermia (n=2); or double ligation and purse-string suture of the PDA with extracorporeal circulation and normothermia on a beating heart (n=1), or with heart-lung machine on standby (n=1). RESULTS: Mortality was nil. The postoperative course was mild in all cases. Follow up 3 to 8 years post surgery showed effective PDA closure, PAP within normal (n=3) or at upper normal limits (n=1), and no other sequelae. CONCLUSIONS: The use of extracorporeal circulation allows safe and uncomplicated surgical closure of a PDA in "difficult" cases. |
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Authors:
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Georgios Kalavrouziotis; Antonios Kourtesis; Christodoulos Paphitis; Prodromos Azariades |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Hellenic journal of cardiology : HJC = Hell?nik? kardiologik? epithe?r?s? Volume: 51 ISSN: 1109-9666 ISO Abbreviation: Hellenic J Cardiol Publication Date: 2010 Jan-Feb |
Date Detail:
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Created Date: 2010-02-01 Completed Date: 2010-05-13 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101257381 Medline TA: Hellenic J Cardiol Country: Greece |
Other Details:
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Languages: eng Pagination: 15-8 Citation Subset: IM |
Affiliation:
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Department of Cardiothoracic Surgery, Aghia Sophia Children's Hospital, Athens, Greece. gkalavrouziotis@yahoo.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Child Ductus Arteriosus, Patent / complications*, surgery* Extracorporeal Circulation* Female Humans Hypertension, Pulmonary / complications* Male Middle Aged Treatment Outcome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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