| Clostridium septicum aortitis: Report of two cases and review of the literature. | |
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MedLine Citation:
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PMID: 19307090 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Clostridium septicum aortitis is a rare infection that has a strong association with occult colonic malignancy. To our knowledge, we report the 25th and 26th cases of C septicum aortitis in the English literature and make recommendations for its management. The first patient was a 75-year-old man who presented with abdominal pain. Computed tomography showed the presence of periaortic gas. He underwent aortic débridement and extra-anatomic bypass after blood cultures revealed C septicum. Four months after the initial presentation, he was readmitted with lethargy, found to have recurrent periaortic gas, and died. The second patient was a 76-year-old woman who presented with a 5-cm abdominal aortic aneurysm with surrounding retroperitoneal gas. She underwent emergency aortic ligation and retroperitoneal débridement. Her blood and intraoperative tissue cultures also grew C septicum. She had a prolonged postoperative course and ultimately died on hospital day 94. Both patients were found to have concurrent colon adenocarcinomas. C septicum aortitis is a lethal disease that necessitates prompt surgical intervention and appropriate antibiotic therapy. The strong association of C septicum with occult malignancy should prompt the astute clinician to undertake an exhaustive search for a neoplastic process. |
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Authors:
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Christopher W Seder; Michael Kramer; Graham Long; Maciej R Uzieblo; Charles J Shanley; Paul Bove |
Publication Detail:
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Type: Case Reports; Journal Article; Review |
Journal Detail:
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Title: Journal of vascular surgery : official publication, the Society for Vascular Surgery [and] International Society for Cardiovascular Surgery, North American Chapter Volume: 49 ISSN: 1097-6809 ISO Abbreviation: J. Vasc. Surg. Publication Date: 2009 May |
Date Detail:
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Created Date: 2009-04-27 Completed Date: 2009-05-07 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8407742 Medline TA: J Vasc Surg Country: United States |
Other Details:
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Languages: eng Pagination: 1304-9 Citation Subset: IM |
Affiliation:
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Department of Surgery, Section of General, Royal Oak, Mich., USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adenocarcinoma
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complications*,
pathology,
surgery Aged Aged, 80 and over Aneurysm, Infected / microbiology*, radiography, therapy Anti-Bacterial Agents / therapeutic use Aortic Aneurysm / microbiology*, radiography, therapy Aortitis / microbiology*, radiography, therapy Blood Vessel Prosthesis Implantation Clostridium Infections / complications, microbiology*, radiography, therapy Clostridium septicum / isolation & purification* Colonic Neoplasms / complications*, pathology, surgery Debridement Digestive System Surgical Procedures Fatal Outcome Female Humans Male Middle Aged Recurrence Tomography, X-Ray Computed Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Anti-Bacterial Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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