Document Detail

Clostridium botulinum and sudden infant death syndrome: a 10 year prospective study.
MedLine Citation:
PMID:  1562366     Owner:  NLM     Status:  MEDLINE    
It has been proposed that sudden and unexpected death in infants due to intestinal infection with Clostridium botulinum may mimic the clinicopathological features of sudden infant death syndrome. Between 3.3 and 3.8% of infants in some series have had this neurotoxin-producing bacterium isolated on faecal culture. Prospective screening of 248 infants presenting with the sudden infant death syndrome to the Adelaide Children's Hospital over a 10 year period from 1981 to 1990 was conducted. Faecal samples were obtained from both small and large intestines and cultured specifically for C. botulinum. No samples were positive. The results of this study suggest that routine post-mortem culture of faeces for C. botulinum has been of limited use within the South Australian infant population over the last decade, and that occult botulism has not been a significant factor in the causation of sudden death.
R W Byard; L Moore; A J Bourne; A J Lawrence; P N Goldwater
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of paediatrics and child health     Volume:  28     ISSN:  1034-4810     ISO Abbreviation:  J Paediatr Child Health     Publication Date:  1992 Apr 
Date Detail:
Created Date:  1992-05-21     Completed Date:  1992-05-21     Revised Date:  2007-09-24    
Medline Journal Info:
Nlm Unique ID:  9005421     Medline TA:  J Paediatr Child Health     Country:  AUSTRALIA    
Other Details:
Languages:  eng     Pagination:  156-7     Citation Subset:  IM    
Department of Histopathology, Adelaide Children's Hospital, Australia.
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MeSH Terms
Botulism / complications*,  microbiology
Clostridium botulinum / isolation & purification*
Infant, Newborn
Prospective Studies
Sudden Infant Death / etiology*

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