Document Detail

Closing the loop for Deep Brain Stimulation implants enables personalized healthcare for Parkinson's disease patients.
MedLine Citation:
PMID:  22254618     Owner:  NLM     Status:  MEDLINE    
DEEP brain stimulation implants have improved life quality for more than 70,000 patients world-wide with diseases like Parkinson's, essential tremor, or obsessive-compulsive disorder where pharmaceutical therapies alone could not offer sufficient relief. Still, optimization and monitoring relies heavily on regular clinical visits, putting a burden on patient's comfort and clinicians. Permanent monitoring and combination with other patient health signals could ultimately lead to a personalized closed-loop therapy with remote quality monitoring. This requires technological improvements on the DBS implants such as integration of recording capabilities for brain activity monitoring, active low-power electronics, rechargeable battery technology, and body sensor networks for integration with e.g. gait, speech, and other vital information sensors on the patient's body and a link to a telemedicine platform using mobile technologies.
Wolfgang Eberle; Julien Penders; Refet Firat Yazicioglu
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference     Volume:  2011     ISSN:  1557-170X     ISO Abbreviation:  Conf Proc IEEE Eng Med Biol Soc     Publication Date:  2011  
Date Detail:
Created Date:  2012-01-18     Completed Date:  2012-06-12     Revised Date:  2014-08-21    
Medline Journal Info:
Nlm Unique ID:  101243413     Medline TA:  Conf Proc IEEE Eng Med Biol Soc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1556-8     Citation Subset:  IM    
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MeSH Terms
Biofeedback, Psychology / instrumentation*
Deep Brain Stimulation / instrumentation*
Diagnosis, Computer-Assisted / instrumentation
Electroencephalography / instrumentation*
Equipment Design
Equipment Failure Analysis
Individualized Medicine / instrumentation*
Parkinson Disease / diagnosis*,  therapy*
Reproducibility of Results
Sensitivity and Specificity
Systems Integration
Therapy, Computer-Assisted / instrumentation*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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