Document Detail

Closed anesthesia with nitrous oxide.
MedLine Citation:
PMID:  9275707     Owner:  NLM     Status:  MEDLINE    
Anesthesia was induced with intravenous thiopental, fentanyl, and succinylcholine, and maintained with isoflurane, N2O-O2 and atracurium after denitrogenation in 20 adult patients. Inspired and end-tidal concentrations of O2, N2O, CO2, isoflurane and oxygen saturation of pulse oximeter (SpO2) were monitored. After intubation, N2O (750 ml/min) and O2 (250 ml/min) were administrated. When inspired N2O concentration (FiN2O) reached 60% the closed anesthesia was initiated by adjusting fresh gas flow rate in order to meet the oxygen demand of the patients. The N2O/O2 ratio was constantly kept at 0.7. The results revealed that during wash-in period, FiN2O increased, on average, to 30% at 3.83 min, 40% at 6.22 min, 50% at 14.13 min respectively. After 30 min of closed anesthesia, FiN2O decreased to 49.4%. It was 46.8% at 60 min. Thereafter it increased smoothly to 51.9% at 180 min. No hypoxia and hypercapnia occurred. Compared with commonly used high flow N2O-N2 inhalation, the technique of low flow wash-in and closed circuit maintenance with N2O-O2 may be less expensive and feasible and causes less pollution.
S Li; Z Wang; B Zeng; J Liu
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of Tongji Medical University = Tong ji yi ke da xue xue bao     Volume:  16     ISSN:  0257-716X     ISO Abbreviation:  J. Tongji Med. Univ.     Publication Date:  1996  
Date Detail:
Created Date:  1997-10-09     Completed Date:  1997-10-09     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8605495     Medline TA:  J Tongji Med Univ     Country:  CHINA    
Other Details:
Languages:  eng     Pagination:  126-8     Citation Subset:  IM    
Department of Anesthesiology, Xiehe Hospital, Tongji Medical University, Wuhan.
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MeSH Terms
Abdomen / surgery
Anesthesia, Closed-Circuit
Anesthetics, Inhalation*
Middle Aged
Nitrous Oxide*
Reg. No./Substance:
0/Anesthetics, Inhalation; 10024-97-2/Nitrous Oxide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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