Document Detail

Close relation between hypothalamic and cardiac norepinephrine during stress and its role in acute myocardial infarction disrhythmias.
MedLine Citation:
PMID:  729729     Owner:  NLM     Status:  MEDLINE    
The decrease of the norepinephrine levels in hypothalamus and heart caused by stress is prevented by pargyline and imipramine. Such a decrease in spleen and adrenals is not affected. Chlorpromazine and lithium only prevented the norepinephrine decrease in the spleen. The uptake of H3norepinephrine by isolated atria of guinea-pig increases during anoxia; the change to a normal oxygen situation decreases these norepinephrine levels by more than 50%.
R Martinez-Sierra; F Andres-Trelles; C V Herrero
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Experientia     Volume:  34     ISSN:  0014-4754     ISO Abbreviation:  Experientia     Publication Date:  1978 Dec 
Date Detail:
Created Date:  1979-03-13     Completed Date:  1979-03-13     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0376547     Medline TA:  Experientia     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  1611-3     Citation Subset:  IM; S    
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MeSH Terms
Adrenal Glands / metabolism
Arrhythmias, Cardiac / etiology*
Hypothalamus / metabolism*
Myocardial Infarction / complications,  metabolism*
Myocardium / metabolism*
Norepinephrine / metabolism*,  physiology
Psychotropic Drugs / pharmacology
Restraint, Physical
Spleen / metabolism
Stress, Physiological / metabolism*
Reg. No./Substance:
0/Psychotropic Drugs; 51-41-2/Norepinephrine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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