| Close correlation between anxiety, depression, and asthma control. | |
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MedLine Citation:
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PMID: 19733042 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: We investigated the correlation between patients' characteristics, including anxiety and depression, and the level of asthma control evaluated by asthma control test (ACT), a self-administered validated questionnaire. METHODS: This is a cross-sectional study on asthmatic outpatients of three Italian hospitals. Demographic data, spirometry, anxiety and depression scores as well as the level of asthma control from 315 patients were collected. RESULTS: Patients with poorly controlled asthma were more frequently women, older, with a worse pulmonary function, obese, more anxious and/or more depressed. Four different independent factors associated with poor asthma control evaluated by ACT have been found: FEV(1)<60% (odds ratio, OR: 6.52), anxiety (OR: 3.76), age > or =65 years (OR: 2.69), and depression (OR: 2.45). The presence of anxiety and depression was associated with a higher healthcare utilization. Finally, we found a high level of agreement between ACT and multidimensional GINA approach in evaluating asthma control, with a concordance in 239 patients (81% of the population). CONCLUSION: There is a close correlation between anxiety and depression, and a poor asthma. A better understanding of this association may have major clinical implications, mainly in patients with poor controlled asthma in whom the presence of anxiety and depression should be investigated. |
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Authors:
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Fabiano Di Marco; Massimo Verga; Pierachille Santus; Francesca Giovannelli; Paolo Busatto; Margherita Neri; Giuseppe Girbino; Sergio Bonini; Stefano Centanni |
Publication Detail:
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Type: Journal Article; Multicenter Study; Validation Studies Date: 2009-09-04 |
Journal Detail:
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Title: Respiratory medicine Volume: 104 ISSN: 1532-3064 ISO Abbreviation: Respir Med Publication Date: 2010 Jan |
Date Detail:
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Created Date: 2010-02-03 Completed Date: 2010-09-09 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8908438 Medline TA: Respir Med Country: England |
Other Details:
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Languages: eng Pagination: 22-8 Citation Subset: IM |
Copyright Information:
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Copyright 2009 Elsevier Ltd. All rights reserved. |
Affiliation:
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Clinica di Malattie dell'Apparato Respiratorio, Ospedale San Paolo, Università degli Studi di Milano, Milano, Italy. fabiano.dimarco@unimi.it |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Anti-Asthmatic Agents / therapeutic use* Anxiety Disorders / complications* Asthma / drug therapy*, psychology Cross-Sectional Studies Depressive Disorder / complications* Female Humans Italy / epidemiology Male Middle Aged Odds Ratio Patient Compliance Quality of Life Questionnaires Self Care / methods Severity of Illness Index |
| Chemical | |
Reg. No./Substance:
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0/Anti-Asthmatic Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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