Document Detail

Clopidogrel use throughout pregnancy in a patient with a drug-eluting coronary stent.
MedLine Citation:
PMID:  21768844     Owner:  NLM     Status:  In-Data-Review    
BACKGROUND: : Little information regarding the potential implications of drug-eluting stents and clopidogrel on pregnancy exists.
CASE: : We report a case of a 27-year-old woman who received a drug-eluting coronary stent for an acute myocardial infarction and was started on clopidogrel as treatment. She was on clopidogrel when she conceived and delivered a child by cesarean. Her postpartum course was complicated by postoperative bleeding requiring transfusion.
CONCLUSION: : This case highlights the perinatal and peripartum concerns of these interventions in women of childbearing age. It suggests that cesarean delivery is associated with an elevated risk of perioperative bleeding and may best be approached like other surgical procedures, with the optimal timing of surgery, when feasible, being 5 or more days after the discontinuation of clopidogrel.
G Robert Myers; Matthew K Hoffman; Erik S Marshall
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  118     ISSN:  1873-233X     ISO Abbreviation:  Obstet Gynecol     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2011-07-19     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  432-3     Citation Subset:  AIM; IM    
From Christiana Care Health System, Newark, Delaware.
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