Document Detail


Cloning of cDNAs coding for rat hepatic microsomal UDP-glucuronyltransferases.
MedLine Citation:
PMID:  2989105     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Radioiodinated, affinity-purified, anti-UDP-glucuronyltransferase (UDPGT) antibodies have been used to isolate cDNAs coding for UDPGT(s) from a rat liver cDNA library cloned in the expression vector bacteriophage lambda gt11. The sizes of ten cloned cDNAs range from 0.3-2.1 kb. The identity of the cDNAs was confirmed by the hybrid-select translation and immunochemical analyses. Restriction mapping indicates that two classes of cDNA coding for different UDPGT mRNAs have been cloned.
Authors:
M R Jackson; L R McCarthy; R B Corser; G C Barr; B Burchell
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Gene     Volume:  34     ISSN:  0378-1119     ISO Abbreviation:  Gene     Publication Date:  1985  
Date Detail:
Created Date:  1985-08-21     Completed Date:  1985-08-21     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7706761     Medline TA:  Gene     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  147-53     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Cloning, Molecular
DNA / genetics
DNA Restriction Enzymes / diagnostic use
DNA, Recombinant
Glucuronosyltransferase / genetics*
Microsomes, Liver / enzymology*
Molecular Weight
Protein Biosynthesis
RNA, Messenger / genetics
Rats
Rats, Inbred Strains
Chemical
Reg. No./Substance:
0/DNA, Recombinant; 0/RNA, Messenger; 9007-49-2/DNA; EC 2.4.1.17/Glucuronosyltransferase; EC 3.1.21.-/DNA Restriction Enzymes

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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