Document Detail

Clonidine premedication decreases hemodynamic responses to pin head-holder application during craniotomy.
MedLine Citation:
PMID:  9585285     Owner:  NLM     Status:  MEDLINE    
IMPLICATIONS: In this study, we investigated an approach to the prevention of increased blood pressure often seen during the early part of anesthesia for brain surgery. Oral clonidine was effective in reducing the mean arterial blood pressure increase resulting from pin head-holder application. Clonidine, a blood pressure-reducing drug, was given to 25 patients before anesthesia. Their blood pressure measurements were then compared with those of 25 patients not given clonidine.
T G Costello; J R Cormack
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Anesthesia and analgesia     Volume:  86     ISSN:  0003-2999     ISO Abbreviation:  Anesth. Analg.     Publication Date:  1998 May 
Date Detail:
Created Date:  1998-05-20     Completed Date:  1998-05-20     Revised Date:  2014-07-29    
Medline Journal Info:
Nlm Unique ID:  1310650     Medline TA:  Anesth Analg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1001-4     Citation Subset:  AIM; IM    
Export Citation:
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MeSH Terms
Anti-Anxiety Agents / pharmacology*
Clonidine / pharmacology*
Double-Blind Method
Hemodynamics / drug effects*
Middle Aged
Preanesthetic Medication*
Prospective Studies
Temazepam / pharmacology*
Reg. No./Substance:
0/Anti-Anxiety Agents; CHB1QD2QSS/Temazepam; MN3L5RMN02/Clonidine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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