| Clonazepam for chemotherapy-induced nausea and vomiting (CINV). | |
| | |
MedLine Citation:
|
PMID: 18751430 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: A 51-year-old woman experienced refractory chemotherapy-induced nausea and vomiting (CINV) in spite of extensive antiemetic therapy, including 5-HT3 antagonists, corticosteroids, dopamine antagonists and antihistamines. CASE REPORT: We administered the patient clonazepam. After taking clonazepam, the patient fully recovered from the nausea and vomiting and never experienced them again. CONCLUSION: Clonazepam may be useful in the control of CINV. We believe that clonazepam contributed to the favorable outcome by expressing an anxiolytic and an anticonvulsant effect on myoclonus. The efficacy of clonazepam in this indication of prevention of CINV warrants further investigation. |
| | |
Authors:
|
Minako Koga; Momoe Nakadozono; Kazutaka Nukariya; Hiroko Nogi; Tadashi Kobayashi; Kazuhiko Nakayama |
Publication Detail:
|
Type: Case Reports; Journal Article |
Journal Detail:
|
Title: Anticancer research Volume: 28 ISSN: 0250-7005 ISO Abbreviation: Anticancer Res. Publication Date: 2008 Jul-Aug |
Date Detail:
|
Created Date: 2008-08-28 Completed Date: 2008-09-09 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8102988 Medline TA: Anticancer Res Country: Greece |
Other Details:
|
Languages: eng Pagination: 2433-6 Citation Subset: IM |
Affiliation:
|
Department of Psychiatry, Machida Municipal Hospital, Machida-shi, Tokyo, 194-0023, Japan. mi-na@pd5.so-net.ne.jp |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Antineoplastic Combined Chemotherapy Protocols
/
adverse effects*,
therapeutic use Breast Neoplasms / drug therapy Clonazepam / therapeutic use* Doxorubicin / administration & dosage, adverse effects Female Humans Middle Aged Nausea / chemically induced, drug therapy* Taxoids / administration & dosage, adverse effects Vomiting / chemically induced, drug therapy* |
| Chemical | |
Reg. No./Substance:
|
0/Taxoids; 114977-28-5/docetaxel; 1622-61-3/Clonazepam; 23214-92-8/Doxorubicin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Predictive markers of radiation pneumonitis.
Next Document: Influence of valproic acid on outcome of high-grade gliomas in children.