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Clonality in Thyroid Nodules: The Hyperplasia-Neoplasia Sequence.
MedLine Citation:
PMID:  12114776     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The evaluation of clonality in nodular proliferations of the thyroid gland has identified a large proportion of monoclonal nodules even in the setting of nonendemic nodular goiter The literature on this topic is reviewed and an attempt is made to explain the available data. In the absence of a clear understanding of the biological impact and potential of these molecular events, a recommendation is made for continued use of current histomorphologic nomenclature when diagnosing such thyroid lesions in the day-to-day practice of surgical pathology.
Authors:
Zubair W. Baloch; Virginia A. LiVolsi
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Publication Detail:
Type:  JOURNAL ARTICLE    
Journal Detail:
Title:  Endocrine pathology     Volume:  9     ISSN:  1559-0097     ISO Abbreviation:  Endocr. Pathol.     Publication Date:  1998  
Date Detail:
Created Date:  2002-Jul-12     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9009288     Medline TA:  Endocr Pathol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  287-292     Citation Subset:  -    
Affiliation:
MD, PhD.
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