Document Detail


Clomiphene citrate stimulation as an adjunct in locating ovarian tissue in ovarian remnant syndrome.
MedLine Citation:
PMID:  2216258     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Ovarian remnant syndrome results from residual ovarian tissue after bilateral oophorectomy. The syndrome is associated with chronic pelvic pain and is suspected when premenopausal levels of FSH and LH are present in a patient with documented bilateral oophorectomy. Histologic demonstration of ovarian tissue at operation confirms the diagnosis. We treated a patient with ovarian remnant syndrome with a 10-day course of clomiphene citrate, 100 mg daily, to stimulate the residual ovarian tissue and facilitate localization. Preoperative ultrasound revealed a 5.0 x 3.5 x 6.2-cm cystic mass in the right adnexal region. Exploratory laparotomy easily localized the mass, and it was removed intact. Histologic slides demonstrated normal ovarian tissue with multiple follicles in various stages of development and a corpus luteum cyst. Clomiphene citrate is capable of stimulating an ovarian remnant, producing an enlarged, cystic structure easily localized by ultrasound. The increased size and preoperative knowledge of the location facilitated surgical removal.
Authors:
P F Kaminski; J I Sorosky; M J Mandell; R P Broadstreet; R J Zaino
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  76     ISSN:  0029-7844     ISO Abbreviation:  Obstet Gynecol     Publication Date:  1990 Nov 
Date Detail:
Created Date:  1990-11-19     Completed Date:  1990-11-19     Revised Date:  2009-10-26    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  924-6     Citation Subset:  AIM; IM    
Affiliation:
Department of Obstetrics and Gynecology, Milton S. Hershey Medical Center, Pennsylvania State University, Hershey.
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MeSH Terms
Descriptor/Qualifier:
Adult
Clomiphene / diagnostic use*
Female
Humans
Ovariectomy*
Ovary* / drug effects,  ultrasonography
Postoperative Complications / ultrasonography*
Reoperation
Stimulation, Chemical
Syndrome
Chemical
Reg. No./Substance:
911-45-5/Clomiphene

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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