Document Detail

Clivus chordoma in a 9-year-old child: case report and review of the literature.
MedLine Citation:
PMID:  3152925     Owner:  NLM     Status:  MEDLINE    
Chordomas are bone tumors of the axial skeleton. They arise from notochordal remnants. In children these tumors are extremely rare and are predominantly located in the skull base. The authors report on a clivus chordoma in a 9 7/12-year-old girl. It presented as a nasopharyngeal mass with destruction of the clivus and paralyses of the ninth, tenth, and eleventh cranial nerves on the right side. After incomplete resection by a transoral transclival route, high-dose radiotherapy was added. This treatment was effective as demonstrated by follow-up CAT scans. A short review of the current literature is given. The local recurrence rate is extremely high, and distant metastases may occur. Complete resection is rarely possible, and combined management with postoperative radiotherapy is propagated. Permanent cure is rare, and at the present time, chemotherapy appears to be of no value in the primary treatment of chordomas.
F M Fink; B Ausserer; W Schröcksnadel; A K Pallua; H Frommhold; G Mikuz
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Pediatric hematology and oncology     Volume:  4     ISSN:  0888-0018     ISO Abbreviation:  Pediatr Hematol Oncol     Publication Date:  1987  
Date Detail:
Created Date:  1990-11-15     Completed Date:  1990-11-15     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8700164     Medline TA:  Pediatr Hematol Oncol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  91-100     Citation Subset:  IM    
Department of Pediatrics, University of Innsbruck, Austria.
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MeSH Terms
Chordoma* / complications,  radiography,  radiotherapy,  surgery
Combined Modality Therapy
Cranial Nerve Diseases / etiology
Nerve Compression Syndromes / etiology
Occipital Bone
Skull Neoplasms* / complications,  radiography,  radiotherapy,  surgery
Sphenoid Bone
Tomography, X-Ray Computed

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