Document Detail


Clinicopathological, ultrasonographic, and histopathological findings of superficial necrolytic dermatitis with hepatopathy in a cat.
MedLine Citation:
PMID:  12549610     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This report describes the antemortem diagnosis and antemortem and postmortem findings of superficial necrolytic dermatitis with hepatopathy (i.e., hepatocutaneous syndrome) in a cat. A 5-year-old Maine coon was evaluated because of a history of pruritic alopecia and liver enzyme elevations. Abdominal ultrasonography revealed a reticular pattern to the hepatic parenchyma. Histopathological findings of the liver were nodular regeneration with bands of vacuolated hepatocytes and bile duct hyperplasia, characteristic of the hepatopathy frequently associated with superficial necrolytic dermatitis. Skin histopathology revealed multifocal parakeratosis, midepidermal spongiosis, and basal cell hyperplasia consistent with superficial necrolytic dermatitis.
Authors:
Susan E Kimmel; Wendy Christiansen; Kevin P Byrne
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of the American Animal Hospital Association     Volume:  39     ISSN:  0587-2871     ISO Abbreviation:  J Am Anim Hosp Assoc     Publication Date:    2003 Jan-Feb
Date Detail:
Created Date:  2003-01-28     Completed Date:  2003-02-11     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0415027     Medline TA:  J Am Anim Hosp Assoc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  23-7     Citation Subset:  IM    
Affiliation:
Department of Clinical Studies, Veterinary Hospital of the University of Pennsylvania, 3900 Delancey Street, Philadelphia, Pennsylvania 19104-6010, USA.
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MeSH Terms
Descriptor/Qualifier:
Alanine Transaminase / blood
Alopecia / etiology,  veterinary
Animals
Cat Diseases / diagnosis*,  pathology,  ultrasonography
Cats
Dermatitis / complications,  diagnosis,  veterinary*
Diagnosis, Differential
Liver Diseases / complications,  diagnosis,  veterinary*
Male
Necrosis
Syndrome
Chemical
Reg. No./Substance:
EC 2.6.1.2/Alanine Transaminase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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