Document Detail

Clinicopathological report of Candida granuloma from an endogenous candidal endophthalmitis.
MedLine Citation:
PMID:  11565254     Owner:  NLM     Status:  MEDLINE    
Fluconazole was reported to be an effective alternative to Amphotericin B for candidal endophthalmitis. However, the dose for systemic use had not been determined and few pathological reports on its use have been published. An epiretinal membrane harvested from a regressed candidal endophthalmitis in a patient treated with fluconazole (200 mg/day) was sent for pathologic study. On the inner side of the retina, a granuloma was found. Fungal debris was found within the center of the granuloma, but an intact fungus was seen next to the granuloma. Pathologic study showed incomplete treatment in this case, although systemic status had improved. The use of systemic fluconazole should be maintained for a longer period of time to treat candidal endophthalmitis.
H K Kou; J W Lin; K C Chang
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Chang Gung medical journal     Volume:  24     ISSN:  2072-0939     ISO Abbreviation:  Chang Gung Med J     Publication Date:  2001 Jul 
Date Detail:
Created Date:  2001-09-21     Completed Date:  2001-10-11     Revised Date:  2008-12-16    
Medline Journal Info:
Nlm Unique ID:  101088034     Medline TA:  Chang Gung Med J     Country:  China (Republic: 1949- )    
Other Details:
Languages:  eng     Pagination:  460-3     Citation Subset:  IM    
Department of Ophthalmology, Chang Gung Memorial Hospital, 123, Tao-Pei Road, Niaosung, Kaohsiung, Taiwan, R.O.C.
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MeSH Terms
Amphotericin B / therapeutic use
Candidiasis / drug therapy,  pathology*
Endophthalmitis / drug therapy,  pathology*
Fluconazole / therapeutic use
Granuloma / pathology*
Middle Aged
Reg. No./Substance:
1397-89-3/Amphotericin B; 86386-73-4/Fluconazole

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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