Document Detail

Clinicopathological findings and echocardiographic prediction of the localisation of bovine endocarditis.
MedLine Citation:
PMID:  21795306     Owner:  NLM     Status:  MEDLINE    
Thirty-six cows with confirmed vegetative endocarditis at postmortem examination were examined in this study. In 33 cows, echocardiography showed lesions of the pulmonic, tricuspid and mitral valves. Ten healthy cows were enrolled in the study as controls. In diseased cows, clinical signs included recurrent fever, dyspnoea, epistaxis, tachycardia, murmurs, weight loss, decreased milk production, jugular and mammary vein distension with palpable pulse, and ventral and submandibular oedema. Laboratory abnormalities included neutrophilic leukocytosis, elevated protein concentrations, hypoalbuminaemia, hypergammaglobulinaemia, azotaemia and elevated serum creatinine concentration. High serum activities of aspartate aminotransferase, γ-glutamyl transpeptidase and lactate dehydrogenase were also detected. Echocardiography showed small, medium-sized or large hyperechogenicity, thickening, and proliferative or vegetative lesions of the tricuspid (n=11), mitral (n=5) and pulmonic valves (n=19). Confirmatory diagnosis was made at postmortem examination. Echocardiography could detect vegetations in 33 of the 36 cows (92 per cent). The sensitivity of ultrasound in detecting valvular endocarditis was 89 per cent for tricuspid valves, 83 per cent for mitral valves and 95 per cent for pulmonic valves.
T Mohamed; S Buczinski
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Publication Detail:
Type:  Journal Article     Date:  2011-07-27
Journal Detail:
Title:  The Veterinary record     Volume:  169     ISSN:  2042-7670     ISO Abbreviation:  Vet. Rec.     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2011-08-15     Completed Date:  2011-10-31     Revised Date:  2012-05-10    
Medline Journal Info:
Nlm Unique ID:  0031164     Medline TA:  Vet Rec     Country:  England    
Other Details:
Languages:  eng     Pagination:  180     Citation Subset:  IM    
Department of Animal Medicine, Faculty of Veterinary Medicine, Zagazig University, PO Box 44511, Egypt.
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MeSH Terms
Aortic Valve / pathology,  ultrasonography
Case-Control Studies
Cattle Diseases / blood,  pathology*,  ultrasonography
Echocardiography / veterinary*
Endocarditis / blood,  pathology,  ultrasonography,  veterinary*
Mitral Valve / pathology,  ultrasonography
Tricuspid Valve / pathology,  ultrasonography

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