| Clinicopathological features of sudden unexpected infectious death: Population-based study in children and young adults. | |
| | |
MedLine Citation:
|
PMID: 22366208 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
INTRODUCTION AND OBJECTIVES: Infectious diseases are one of the major causes of sudden death, but data of sudden unexpected death from infectious diseases (SUDID) are sparse in children and young people. The aim of this study is to analyse their epidemiological, clinical, pathological and microbiological characteristics. METHODS: Population observational study of all deaths due to infectious diseases in people aged 0-34 years in Biscay between 1991 and 2010. The data of Mortality Register and Forensic Pathology Service were analysed. The SUDID cases in which a forensic autopsy was performed were identified. RESULTS: There were 56 SUDID cases (16% of the all sudden deaths). Myocarditis (n=20) and acute bacterial bronchopneumonia/pneumonia (n=18) were the most frequent causes, followed by meningococcemia (n=5) and viral pneumonia (n=4). A chronic co-morbid condition (mainly drug abuse in young people and moderate low birth weight in infants) was recorded in one-third and prodromal symptoms in two-thirds. Seventeen young people had consumed illegal drugs and/or methadone. In 17 of the 23 autopsies where microbiological analyses were performed, the organism responsible was identified. The incidence of SUDID was 0.6/100000 inhabitants/year, representing 5% of all deaths from infectious diseases. SUDID rate was 1.87 times higher in males than in females. The highest incidence occurred in infants (3.7). CONCLUSIONS: SUDID is infrequent, but it represents a significant proportion of all sudden deaths in children and young people. The relationship between methadone and bronchopneumonia is noticeable. This article stresses the importance of microbiological analyses in SUDID. Investigation based on forensic pathology provides useful epidemiologic, clinico-pathological and microbiological information for prevention of infectious diseases. |
| | |
Authors:
|
Benito Morentin; M Paz Suárez-Mier; Beatriz Aguilera; Jon Arrieta; Covadonga Audicana; Amparo Fernández-Rodríguez |
Related Documents
:
|
16146668 - First appropriate use of automated external defibrillator in an infant. 17141868 - Foliar co2 fixation in bean (phaseolus vulgaris l.) submitted to elevated ozone: distin... 3942358 - Sudden unexpected death: intervention with the survivors. 17465148 - Patterns of sexual recruitment of acroporid coral populations on the west fore reef at ... 832018 - Influence of simultaneous low amniotomy and oxytocin infusion and other maternal factor... 7595828 - Radiological decompression of bowel gas and return of mediastinal shift in congenital d... |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2012-2-24 |
Journal Detail:
|
Title: Forensic science international Volume: - ISSN: 1872-6283 ISO Abbreviation: - Publication Date: 2012 Feb |
Date Detail:
|
Created Date: 2012-2-27 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 7902034 Medline TA: Forensic Sci Int Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
Copyright © 2012 Elsevier Ireland Ltd. All rights reserved. |
Affiliation:
|
Forensic Pathology Service, Basque Institute of Legal Medicine, Bilbao, Spain. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Pulmonary mycobacterium abscessus: A canary in the cystic fibrosis coalmine.
Next Document: Arabidopsis Hexokinase-Like1 and Hexokinase1 Form a Critical Node in Mediating Plant Glucose and Eth...