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Clinicopathological correlates of pediatric head and neck cancer.
MedLine Citation:
PMID:  19841559     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
BACKGROUND: The spectrum of head and neck tumors in children continues to be the cause of diverse, diagnostically challenging issues. AIMS: To demonstrate and compare the unique clinicopathological features in our study population and their correlations with the final histopathological diagnosis. METHODS: Fifty-three children with head and neck cancer were examined thoroughly at the Otorhinolaryngology department in a tertiary care teaching hospital followed by histopathological studies. RESULTS: Lymphomas were the most common malignant lesions seen followed by rhabdomyosarcomas, nasopharyngeal carcinomas, and others like thyroid carcinomas and eosinophilic granulomas. In the neck, the commonest cause of primary malignant disease was lymphoma; however, the most frequent lesion was reactive lymphadenitis. In the sinonasal region, the commonest malignancy was rhabdomyosarcoma, which often had extension to the orbit and the face. Recurrent epistaxis was found universally in the malignant cases of this region. In the facial region, disfiguring swelling with proptosis was mainly caused by rhabdomyosarcoma. The only case of tonsillar malignancy was due to non-Hodgkin lymphoma. The duration of disease was less than 1 year. CONCLUSION: The most common manifestation of the malignant lesions in the pediatric age group was with a history of an enlarging, painless neck swelling. Still, an insignificant lump in the neck or recurrent bleeding from nose may be the manifestation of an underlying cancer.
Authors:
Subhabrata Sengupta; Ranabir Pal
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of cancer research and therapeutics     Volume:  5     ISSN:  1998-4138     ISO Abbreviation:  -     Publication Date:    2009 Jul-Sep
Date Detail:
Created Date:  2009-10-20     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101249598     Medline TA:  J Cancer Res Ther     Country:  India    
Other Details:
Languages:  eng     Pagination:  181-5     Citation Subset:  IM    
Affiliation:
Department of Community Medicine, Sikkim-Manipal Institute of Medical Sciences and Central Referral Hospital, Sikkim, India.
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