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Clinicopathological analysis of rhabdoid meningiomas: report of 12 cases and a systematic review of the literature.
MedLine Citation:
PMID:  22902360     Owner:  NLM     Status:  Publisher    
OBJECTIVE: Rhabdoid meningioma (RMs) is a rare sub-type of meningiomas, classified as WHO grade III with poor prognosis. Here we present our experience on RMs and reviewed relevant literatures in an attempt to investigate the clinical features, treatment and prognosis of these tumors. METHODS: 12 patients underwent surgical treatment for intracranial RMs between 2003 and 2008 in our department. The clinical data, radiological manifestation, pathological findings, treatment and prognosis of the patients were analyzed retrospectively. Other 58 cases reported previously by other institutions were also summarized and reviewed. RESULTS: These cases (6 men and 6 women, mean age was 44.3 years old, ranging from 21 to 78 years old) constituted 0.28% of all meningioma patients admitted at our department during the same period. The mean duration of symptoms was relatively short at 1.6 months. There was no significant clinical manifestation noticed, and the radiologic findings fell in three types of images. In the follow-up period over 30 months, 7 patients died, of which recurrence occurred in 5 cases, and 2 patients died of unknown causes. CONCLUSION: 1) Rhabdoid meningioma is a rare subtype of malignant meningioma featured by an increased tendency for recurrence and possible metastasis. 2) It is still difficult to make a correct pre-operative diagnosis. 3) Overall prognosis of these patients is extremely poor, and the role of various adjuvant treatments needs to be further studied.
Yu Zhou; Qing Xie; Ye Gong; Ying Mao; Ping Zhong; Xiaoming Che; Chengchuan Jiang; Fengping Huang; Kang Zheng; Shiqi Li; Yuxiang Gu; Weimin Bao; Bojie Yang; Jinsong Wu; Yin Wang; Hong Chen; Liqian Xie; Mingzhe Zheng; Hailiang Tang; Daijun Wang; Hongda Zhu; Xiancheng Chen
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-8-14
Journal Detail:
Title:  World neurosurgery     Volume:  -     ISSN:  1878-8750     ISO Abbreviation:  World Neurosurg     Publication Date:  2012 Aug 
Date Detail:
Created Date:  2012-8-20     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101528275     Medline TA:  World Neurosurg     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012. Published by Elsevier Inc.
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