Document Detail


Clinico-radiological spectrum of bilateral temporal lobe hyperintensity: a retrospective review.
MedLine Citation:
PMID:  22422381     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Bilateral temporal lobe hyperintensity (BTH) is a commonly encountered MRI finding in a wide spectrum of clinical conditions and often poses a diagnostic challenge to the radiologist. The purpose of this paper is to elucidate several diseases that manifest as BTH on MRI, based on a retrospective review of cranial MRI of 65 cases seen in our institution between October 2007 and September 2010. We found BTH in different clinical scenarios that included infective diseases (herpes simplex virus, congenital cytomegalovirus infection), epileptic syndrome (mesial temporal sclerosis), neurodegenerative disorders (Alzheimer's disease, frontotemporal dementia, Type 1 myotonic dystrophy), neoplastic conditions (gliomatosis cerebri), metabolic disorders (mitochondrial encephalopathy, lactic acidosis and stroke-like episodes, Wilson's disease, hyperammonemia), dysmyelinating disease (megalencephalic leukoencephalopathy with subcortical cysts), and vascular (cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy) and paraneoplastic (limbic encephalitis) disorders. The conventional MRI findings with advanced MRI such as diffusion-weighted imaging, susceptibility-weighted imaging and MR spectroscopy along with laboratory results are potentially helpful in distinguishing the different clinical conditions and thus affect the early diagnosis and clinical outcome.
Authors:
J Sureka; R K Jakkani
Publication Detail:
Type:  Journal Article; Review     Date:  2012-03-14
Journal Detail:
Title:  The British journal of radiology     Volume:  85     ISSN:  1748-880X     ISO Abbreviation:  Br J Radiol     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-08-24     Completed Date:  2012-11-05     Revised Date:  2013-09-03    
Medline Journal Info:
Nlm Unique ID:  0373125     Medline TA:  Br J Radiol     Country:  England    
Other Details:
Languages:  eng     Pagination:  e782-92     Citation Subset:  AIM; IM    
Affiliation:
Department of Radiology, Christian Medical College and Hospital, Vellore, Tamilnadu, India. drjyoticmch@rediffmail.com
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Child
Encephalitis / pathology*
Female
Humans
Magnetic Resonance Imaging / methods*
Male
Middle Aged
Neurodegenerative Diseases / pathology*
Retrospective Studies
Stroke / pathology*
Temporal Lobe / pathology*
Young Adult
Comments/Corrections

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