Document Detail

Clinico-pathological studies on a transitional type between extrahepatic biliary atresia and paucity of the interlobular bile ducts.
MedLine Citation:
PMID:  8318784     Owner:  NLM     Status:  MEDLINE    
Among the neonatal and infantile cases of obstructive jaundice seen at Niigata and Yamagata University Hospitals between 1976 and 1990, extrahepatic bile ducts were visualized in 19 cases by either preoperative endoscopic retrograde cholangiopancreaticography (ERCP) or intraoperative cholangiography. Neonatal hepatitis was diagnosed in 3 of these cases by clear images of the bile duct system extending from the common bile duct to the intrahepatic bile duct. In 7 cases, the common bile duct was able to be seen, while the common hepatic duct was only slightly visualized. Four of these 7 cases were consistent with paucity of the interlobular bile ducts (PILBD) based on hepatic histology, while the remaining 3 showed fibrosis, bile ductular proliferation, and many bile plugs in the bile ductuli of the portal areas, concurrent with histological changes in extrahepatic biliary atresia (EHBA), not PILBD. In 9 cases, only the common bile duct was visualized while the common hepatic duct was not seen, 7 of these 9 cases being consistent with type III-a1 EHBA. In 2 cases, neither fibrosis nor proliferation of the bile ductuli was observed in the portal areas, and portal areas without any bile ductuli were also seen, in accordance with findings for PILBD. Three cases which showed similar hepatic histological findings to EHBA despite the presence of patent extrahepatic bile ducts, and 2 cases which had obstructed extrahepatic bile ducts and hepatic histological findings similar to PILBD, were thought to be of a transitional type between EHBA and PILBD.(ABSTRACT TRUNCATED AT 250 WORDS)
I Yamagiwa; K Obata; Y Hatanaka; H Saito; M Washio; M Iwafuchi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Surgery today     Volume:  23     ISSN:  0941-1291     ISO Abbreviation:  Surg. Today     Publication Date:  1993  
Date Detail:
Created Date:  1993-08-05     Completed Date:  1993-08-05     Revised Date:  2006-08-03    
Medline Journal Info:
Nlm Unique ID:  9204360     Medline TA:  Surg Today     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  307-14     Citation Subset:  IM    
Second Department of Surgery, Yamagata University School of Medicine, Japan.
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MeSH Terms
Bile Duct Diseases / diagnosis
Bile Ducts, Intrahepatic / radiography*
Biliary Atresia / complications,  diagnosis*,  surgery
Cholangiopancreatography, Endoscopic Retrograde
Cholestasis, Extrahepatic / complications,  diagnosis*,  surgery
Common Bile Duct / radiography*
Hepatic Duct, Common*
Infant, Newborn
Liver / pathology*

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