|Clinico-pathological features of cystic pancreatic endocrine neoplasms and a comparison with their solid counterparts.|
|PMID: 16580809 Owner: NLM Status: MEDLINE|
|AIM: Pancreatic endocrine neoplasms (PENs) may occasionally manifest as cystic lesions of the pancreas. The aim of this study is to report our experience with cystic PENs and to compare their clinico-pathological features with their solid counterparts. MATERIALS AND METHODS: From 1990 to 2004, 38 patients with PENs were reviewed. Six of these tumours appeared on radiological imaging as a cystic lesion of the pancreas. RESULTS: Of the 38 patients with a PEN, 21 of the patients were female and with a median age of 54.5 (range, 33-83) years. Sixteen patients had functional endocrine tumours of which insulinoma was the most common. The six patients with cystic PEN had a median age of 55.5 (range, 41-70) years and half were female. Cystic PENs were significantly larger [48 (range, 25-170) mm vs 19 (range, 3-120) mm, P = 0.013] and were less likely to be benign (0 vs 50%, P = 0.017) compared to their solid counterparts. There was no difference between cystic and solid PENs in terms of age, sex, presence of symptoms, proportion of functioning tumours and location of tumours within the pancreas. CONCLUSION: Cystic PENs share many clinico-pathological features with solid PENs. These differ only in the cystic appearance and tend to be of a larger size. Hence, these findings suggest that cystic and solid PENs are unlikely to be distinct pathological entities but are likely to be morphological variants of the same entity.|
|B K P Goh; L L P J Ooi; Y M Tan; P C Cheow; Y F A Chung; P K H Chow; W K Wong|
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|Type: Comparative Study; Journal Article Date: 2006-04-03|
|Title: European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology Volume: 32 ISSN: 0748-7983 ISO Abbreviation: Eur J Surg Oncol Publication Date: 2006 Jun|
|Created Date: 2006-05-29 Completed Date: 2006-08-11 Revised Date: 2007-07-02|
Medline Journal Info:
|Nlm Unique ID: 8504356 Medline TA: Eur J Surg Oncol Country: England|
|Languages: eng Pagination: 553-6 Citation Subset: IM|
|Department of Surgery, Singapore General Hospital, Singapore.|
|APA/MLA Format Download EndNote Download BibTex|
Aged, 80 and over
Gastrinoma / pathology
Insulinoma / pathology
Multiple Endocrine Neoplasia Type 1 / pathology
Neoplasms, Multiple Primary / pathology
Pancreatic Cyst / pathology
Pancreatic Neoplasms / pathology*
Stomach Neoplasms / pathology
Tomography, X-Ray Computed
Vipoma / pathology
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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