Document Detail

Clinico-biochemical, immunological, and morphological assessment of myocardial inflammatory reactions in myocardial necroses.
MedLine Citation:
PMID:  1212869     Owner:  NLM     Status:  MEDLINE    
In 328 patients with myocardial infarction, changes were followed occurring in the levels of haptoglobin (Hp) and chloride-soluble mucoprotein (CMP), heterogeneity of mucoprotein, and titres of anticardial antibodies. From the 2nd-3rd days after infarction, the levels of Hp, CMP, and 3rd and 4th mucoprotein fractions increased and remained elevated for 4 weeks; then the levels gradually sank, and normalized in the 7th-8th weeks after infarction. The anticardial antibody titres remained high from the 3rd to the 6th weeks. In 37 patients who died, the clinico-biochemical, immunobiological, and morphological findings were compared. It was found that assessments of the Hp and CMP levels as well as of mucoprotein heterogeneity make it possible to appraise the intensity of inflammatory reaction in myocardial necroses and thus facilitate the choice of differentiated antiinflammatory treatment of patients with myocardial infarction.
S V Shestakov; V N Fatenkov; B L Movshovich; T A Naddachina; V M Rusakov
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cor et vasa     Volume:  17     ISSN:  0010-8650     ISO Abbreviation:  Cor Vasa     Publication Date:  1975  
Date Detail:
Created Date:  1976-04-15     Completed Date:  1976-04-15     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372614     Medline TA:  Cor Vasa     Country:  CZECHOSLOVAKIA    
Other Details:
Languages:  eng     Pagination:  254-61     Citation Subset:  IM    
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MeSH Terms
Antibodies / analysis
Glycoproteins / blood
Haptoglobins / blood
Mucoproteins / blood
Myocardial Infarction / blood,  immunology,  pathology*
Myocardium / immunology,  pathology*
Reg. No./Substance:
0/Antibodies; 0/Glycoproteins; 0/Haptoglobins; 0/Mucoproteins

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