| Clinically unrecognized pulmonary aspiration during gastrointestinal endoscopy with sedation: A potential pitfall interfering the performance of (18)F-FDG PET for cancer screening. | |
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MedLine Citation:
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PMID: 21439750 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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PURPOSE: We found several cases with unexpected pulmonary abnormalities on the (18)F-FDG PET scan after the gastrointestinal endoscopy with sedation during a compact health check-up course, interfering the interpretations of (18)F-FDG PET scan for cancer screening. The current studies aimed to analyze the incidence and the clinical relevance of this pulmonary finding. MATERIALS AND METHODS: From June to December 2009, 127 subjects undergoing the sequential gastrointestinal endoscopy with sedation and (18)F-FDG PET scan within 48h as part of routine health check-up were retrospectively enrolled in this study. The incidence of abnormal pulmonary findings and their SUV(max) of FDG were calculated and correlated with the clinical manifestations. RESULTS: Five subjects had abnormal (18)F-FDG PET findings but pulmonary symptoms were only found in 2. The SUV(max) did not seem to reflect the severity of pulmonary symptoms or the need of intervention. Although the incidence of unrecognized pulmonary aspiration featuring inflammation detected by the (18)F-FDG PET scan was high (3.94%, 5/127), the incidence of events needed intervention remained low (0.79%, 1/127), similar to those previously reported literatures. CONCLUSIONS: Although higher incidence of pulmonary aspiration in this study, it probably reflects the better sensitivity of (18)F-FDG PET for inflammation. The low incidence of clinical events needed intervention may still reflect the safety of sedation used for gastrointestinal endoscopy. Proper arrangement of the sequential examinations if subjects need both gastrointestinal endoscopy with sedation and (18)F-FDG PET is important to reduce the interference degrading the performance of (18)F-FDG PET in cancer screening, diagnosis or staging. |
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Authors:
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Te-Chun Hsieh; Yu-Chin Wu; Hueisch-Jy Ding; Chih-Hsiu Wang; Kuo-Yang Yen; Shung-Shung Sun; Jun-Jun Yeh; Chia-Hung Kao |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-3-23 |
Journal Detail:
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Title: European journal of radiology Volume: - ISSN: 1872-7727 ISO Abbreviation: - Publication Date: 2011 Mar |
Date Detail:
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Created Date: 2011-3-28 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8106411 Medline TA: Eur J Radiol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2011. Published by Elsevier Ireland Ltd. |
Affiliation:
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Department of Nuclear Medicine and PET Center, China Medical University and Hospital, No. 2, Yuh-Der Road, Taichung 404, Taiwan; Department of Biomedical Imaging and Radiological Science, China Medical University and Hospital, No. 2, Yuh-Der Road, Taichung 404, Taiwan. |
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