| Clinically successful late recanalization of basilar artery occlusion in childhood: what are the odds? Case report and review of the literature. | |
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MedLine Citation:
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PMID: 17482211 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND AND PURPOSE: Acute basilar artery occlusion is an infrequent but potentially fatal cause of stroke, both in adults and children. We present our experience with a 6-year-old child and we investigate the rationality for late treatment of acute basilar occlusion in children. METHODS: We report the case of a 6-year-old boy with acute basilar artery occlusion presented with a full blown locked-in syndrome, admitted to the endovascular suite 44 h after the stroke onset, and we review all the reported cases of basilar artery occlusions presented with locked-in syndrome in children. RESULTS: Six hours following admission the basilar artery was partially recanalized by intra-arterial thrombolysis combined with mechanical clot angioplasty. After 12 h, the patient was awake, oriented, his speech function was fully restored and he had only a mild right hemiparesis that recovered completely after a month. CONCLUSIONS: To our knowledge, this is the first report of complete clinical recovery after delayed (50 h) endovascular recanalization of basilar artery in a child. Intra-arterial thrombolysis combined with cerebral angioplasty, can successfully restore the patency of the basilar artery and the neurologic deficit of children with acute basilar artery occlusion, even after a considerable delay. |
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Authors:
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Savvas Grigoriadis; John Mose Gomori; Nikolaos Grigoriadis; José E Cohen |
Publication Detail:
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Type: Case Reports; Journal Article Date: 2007-05-04 |
Journal Detail:
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Title: Journal of the neurological sciences Volume: 260 ISSN: 0022-510X ISO Abbreviation: J. Neurol. Sci. Publication Date: 2007 Sep |
Date Detail:
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Created Date: 2007-08-13 Completed Date: 2007-12-06 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 0375403 Medline TA: J Neurol Sci Country: Netherlands |
Other Details:
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Languages: eng Pagination: 256-60 Citation Subset: IM |
Affiliation:
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Hadassah Stroke Center, Hadassah University Hospital, Jerusalem, Israel. neurosavas@yahoo.gr |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Age Factors Angioplasty, Balloon / methods*, trends Anticoagulants / administration & dosage Basilar Artery / pathology, radiography, surgery* Brain Stem Infarctions / etiology, pathology, therapy* Child Heparin / administration & dosage Humans Male Pons / blood supply, pathology, physiopathology Quadriplegia / etiology, pathology, therapy Thrombolytic Therapy / methods*, trends Time Factors Treatment Outcome Urokinase-Type Plasminogen Activator / administration & dosage Vertebrobasilar Insufficiency / complications, pathology, therapy* |
| Chemical | |
Reg. No./Substance:
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0/Anticoagulants; 9005-49-6/Heparin; EC 3.4.21.73/Urokinase-Type Plasminogen Activator |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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