Document Detail


Clinically overt and silent cerebral embolism in the course of infective endocarditis.
MedLine Citation:
PMID:  21222127     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The data on cerebral embolism prevalence in the course of infective endocarditis (IE) are most probably underestimated. Part of the cerebral embolism episodes are clinically silent. The objective of this study was to assess the prevalence of clinically silent cerebral embolism in the course of IE and to correlate hematological, inflammatory, and echocardiography parameters with the presence of clinically overt or silent cerebral embolisms. For this purpose, we examined 65 patients with IE by blood test, cultures, echocardiography, and MRI/CT imaging. Clinically overt cerebral embolism was found in 13 patients; 52 patients had no clinically overt cerebral embolism. MRI/CT examinations revealed that among patients with no clinically overt cerebral embolism, 24 had clinically silent cerebral embolism. Thus, 37 patients in all were diagnosed with a cerebral embolism episode (overt + clinically silent). Clinically silent cerebral embolism was diagnosed in 36.9% of all patients, being as high as 64.8% of cerebral embolism cases. Silent or overt embolism development did not depend on the localization of the inflammatory process in either native or artificial valves. The type of cerebral embolism was not found to be influenced by leukocytosis, platelet count, ESR, or hsCRP levels. Neither was the type of embolism found to be influenced by the etiologic factor. Nine patients died. In three patients, the cause of death was hemorrhage from a cerebral apoplectic focus. These results suggest that clinically silent central nervous system embolism is a common complication of infective endocarditis and each patient should undergo a neuroimaging examination.
Authors:
Maciej Grabowski; Tomasz Hryniewiecki; Jadwiga Janas; Janina Stępińska
Related Documents :
2765677 - Clinical significance of fibrinopeptide a in acute lymphocytic and non-lymphocytic leuk...
402187 - Effect of thymosin in vitro on t cell levels during radiation therapy: correlations wit...
2686597 - In vivo and in vitro suppression of lymphocyte function in aspergillus sinusitis.
214047 - A longitudinal study of in vitro tests for lymphocyte function in rheumatoid arthritis.
24613007 - A statistical methodology to improve accuracy in differentiating schizophrenia patients...
10561137 - Hyperleptinemia in uremic patients undergoing conservative management, peritoneal dialy...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-1-11
Journal Detail:
Title:  Journal of neurology     Volume:  -     ISSN:  1432-1459     ISO Abbreviation:  -     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2011-1-11     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0423161     Medline TA:  J Neurol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Valvular Heart Disease, Institute of Cardiology, ul. Alpejska 42, 04-628, Warsaw, Poland, grabi71@yahoo.com.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Digital comparison of planned and implanted stem position in total hip replacement using a program f...
Next Document:  Effect of branched-chain amino acid supplementation during unloading on regulatory components of pro...