Document Detail

Clinical ventilation imaging with In-113m aerosol: a comparison with Kr-81m.
MedLine Citation:
PMID:  7069494     Owner:  NLM     Status:  MEDLINE    
Following routine ventilation (Kr-81m)/perfusion (Tc-99m) scanning, we obtained aerosol ventilation scans using a solution of In-113m albumin and a settling-bag system. The large-volume settling bag reduces deposition of particles in the large airway by removing large droplets. The patient inhales the aerosol with 5-10 min of tidal breathing, then lung scans are obtained on a gamma camera. The energy of In-113m allows the ventilation scanning to be performed after Tc-99m perfusion scanning. Semiquantitative scoring of regional ventilation showed a close correlation (r = 0.97) between Kr-81m and In-113m aerosol ventilation scans. The aerosol technique gave a slight underestimation of ventilation compared with Kr-81m. This is explained by a slightly reduced penetration of particles to the periphery of the lung in patients with severe obstructive airways disease. In all cases, however, the aerosol did visualize all ventilated regions. The results indicate that this readily available aerosol technique can be useful for clinical ventilation imaging in multiple views.
F Fazio; P Wollmer; J P Lavender; M M Barr
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Publication Detail:
Type:  Case Reports; Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of nuclear medicine : official publication, Society of Nuclear Medicine     Volume:  23     ISSN:  0161-5505     ISO Abbreviation:  J. Nucl. Med.     Publication Date:  1982 Apr 
Date Detail:
Created Date:  1982-06-14     Completed Date:  1982-06-14     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0217410     Medline TA:  J Nucl Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  306-14     Citation Subset:  IM    
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MeSH Terms
Airway Obstruction / radionuclide imaging
Bronchitis / radionuclide imaging
Evaluation Studies as Topic
Indium / administration & dosage,  diagnostic use*
Krypton / administration & dosage,  diagnostic use*
Lung / blood supply,  physiology,  radionuclide imaging*
Middle Aged
Pulmonary Embolism / radionuclide imaging*
Radioisotopes / diagnostic use
Technetium / diagnostic use
Tidal Volume
Ventilation-Perfusion Ratio
Reg. No./Substance:
0/Aerosols; 0/Radioisotopes; 7439-90-9/Krypton; 7440-26-8/Technetium; 7440-74-6/Indium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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