Document Detail


Clinical value of carotid wave intensity analysis for differentiating nonobstructive hypertrophic cardiomyopathy from left ventricular hypertrophy secondary to systemic hypertension.
MedLine Citation:
PMID:  23192734     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
PURPOSE.: Wave intensity (WI) is a set of new hemodynamic indexes (W(1) , W(2) , and NA) based on the calculation of (dp/dt) × (dv/dt) on any artery. We assessed the value of carotid WI analysis for differentiating nonobstructive hypertrophic cardiomyopathy (NOHCM) from left ventricular hypertrophy secondary to hypertension (LVHSH). METHODS.: Nineteen NOHCM, 34 LVHSH, and 37 normal controls (NC) underwent conventional echocardiographic examination and carotid WI analysis performed with an Aloka α10 sonographic system (Alok, Tokyo, Japan) with real-time wave intensity calculation software. RESULTS.: W(1) was higher in NOHCM (11,830 ± 7,850 mmHg·m·s(-3) ) and in LVHSH (13,670 ± 13,490 mmHg·m·s(-3) ) than in NC (7,010 ± 3,620 mmHg·m·s(-3) ). W(2) was lower in NOHCM (850 ± 870 mmHg·m·s(-3) ) than in LVHSH (2,310 ± 1,390 mmHg·m·s(-3) , p < 0.01) and in NC (1,650 ± 960 mmHg·m·s(-3) , p < 0.01). Using W(2) ≤ 1,100 mmHg·m·s(-3) as a threshold for differentiating NOHCM from LVHSH yielded an 84.2% sensitivity and 82.4% specificity. NA was higher in LVHSH (57.55 ± 57.82 mmHg·m·s(-2) ) than in NOHCM (34.24 ± 13.03 mmHg·m·s(-2) , p < 0.05) and in NC (31.67 ± 23.05 mmHg·m·s(-2) , p < 0.05). Using NA ≤40 mmHg·m·s(-2) as a threshold for differentiating NOHCM from LVHSH yielded a 63.2% sensitivity and 70.6% specificity. CONCLUSIONS.: W(2) and NA indexes derived from carotid WI analysis may be helpful for differentiating NOHCM from LVHSH. © 2012 Wiley Periodicals, Inc. J Clin Ultrasound, 2012.
Authors:
Yue Li; Liang Guo
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-11-28
Journal Detail:
Title:  Journal of clinical ultrasound : JCU     Volume:  -     ISSN:  1097-0096     ISO Abbreviation:  J Clin Ultrasound     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-29     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0401663     Medline TA:  J Clin Ultrasound     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 Wiley Periodicals, Inc.
Affiliation:
Ultrasound Department of Chinese PLA General Hospital, 28 Fuxing Road, Beijing, 100853, China.
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