Document Detail


Clinical value of N-acetyl-beta-D-glucosaminidase and alpha-galactosidase in liver diseases
MedLine Citation:
PMID:  6269308     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
N-acetyl-beta-D-glucosaminidase is a lysosomal glycosidase, which participates in the catabolism of the mucopolysaccharides and of the glycoproteins. For the determination of this enzyme the production of the substrate and a modified methodology are described. Measurements of the activity were performed by 4-nitrophenyl-alpha-D-galactopyranoside and 4-nitrophenyl-N-acetyl-beta-D-glucosaminide as substrates. Examinations of this enzyme were performed in patients with acute virus hepatitis, chronic hepatitis, liver cirrhosis and healthy test persons. In acute hepatitis and liver cirrhosis and significant increase of enzyme is provable, but not in protracted hepatitis.
Authors:
A Hempel; G Müller; R D Hempel
Publication Detail:
Type:  English Abstract; Journal Article    
Journal Detail:
Title:  Zeitschrift für die gesamte innere Medizin und ihre Grenzgebiete     Volume:  36     ISSN:  0044-2542     ISO Abbreviation:  Z Gesamte Inn Med     Publication Date:  1981 Jul 
Date Detail:
Created Date:  1981-11-22     Completed Date:  1981-11-22     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  21730470R     Medline TA:  Z Gesamte Inn Med     Country:  GERMANY, EAST    
Other Details:
Languages:  ger     Pagination:  457-9     Citation Subset:  IM    
Vernacular Title:
Zur klinischen Wertigkeit der N-Azetyl-beta-D-Glukosamminidase and alpha-Galaktosidase bei Lebererkrankungen.
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MeSH Terms
Descriptor/Qualifier:
Acetylglucosaminidase / blood*
Galactosidases / blood*
Hepatitis, Viral, Human / enzymology
Hexosaminidases / blood*
Humans
Liver Cirrhosis / enzymology
Liver Diseases / enzymology*
Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase
alpha-Galactosidase / blood*
Chemical
Reg. No./Substance:
EC 3.2.1.-/Galactosidases; EC 3.2.1.-/Hexosaminidases; EC 3.2.1.22/alpha-Galactosidase; EC 3.2.1.52/Acetylglucosaminidase; EC 3.2.1.96/Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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