| Clinical value of 99mTc-HMPAO SPECT in depressed bipolar I patients. | |
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MedLine Citation:
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PMID: 15664800 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Regional cerebral blood flow was studied in 17 bipolar I depressed patients (DSM-IV criteria) with single photon emission computed tomography (SPECT). Visual analysis of images revealed no abnormality in eight patients and abnormal findings in nine patients. In the nine patients with abnormal findings, all showed regional decreases of the uptake of (99m)Tc-D,L-hexamethylpropylene amine oxime (HMPAO, four in the frontal region, two in the basal ganglia, and three in both the frontal region and the basal ganglia). The patients with visible SPECT abnormalities had significantly higher scores on the Hamilton Rating Scale for Depression (HDRS). |
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Authors:
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Antoni Benabarre; Eduard Vieta; Francisco Martín; Francisco Lomeña; Anabel Martínez-Aràn; Francesc Colom; Barbara Corbella; Cristóbal Gastó; Manuel Valdés |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Psychiatry research Volume: 132 ISSN: 0165-1781 ISO Abbreviation: Psychiatry Res Publication Date: 2004 Dec |
Date Detail:
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Created Date: 2005-01-24 Completed Date: 2005-03-31 Revised Date: 2008-04-17 |
Medline Journal Info:
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Nlm Unique ID: 7911385 Medline TA: Psychiatry Res Country: Ireland |
Other Details:
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Languages: eng Pagination: 285-9 Citation Subset: IM |
Affiliation:
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Institut Clínic de Psiquiatria i Psicologia, Bipolar Disorders Program, Hospital Clinic, University of Barcelona, IDIBAPS, C/Villarroel 170, 08036 Barcelona, Spain. 31555abh@comb.es |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Basal Ganglia / blood supply Bipolar Disorder / diagnosis* Brain / blood supply* Diagnostic and Statistical Manual of Mental Disorders Female Frontal Lobe / blood supply Humans Male Middle Aged Radiopharmaceuticals / diagnostic use* Regional Blood Flow Technetium Tc 99m Exametazime / diagnostic use* Tomography, Emission-Computed, Single-Photon* |
| Chemical | |
Reg. No./Substance:
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0/Radiopharmaceuticals; 100504-35-6/Technetium Tc 99m Exametazime |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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