Document Detail


Clinical validation and risk factors for delayed gastric emptying based on the International Study Group of Pancreatic Surgery (ISGPS) Classification.
MedLine Citation:
PMID:  19744455     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Delayed gastric emptying (DGE) is one of the most common complications after pancreatoduodenectomy (PD). Because an objective, universally accepted definition of DGE does not yet exist, it is impossible to compare complication rates and outcomes of new operative approaches, operative techniques, and clinical trials. The International Study Group of Pancreatic Surgery (ISGPS) has proposed a universal classification for DGE based on clinical outcomes, but this classification has not been tested rigorously and applied to clinical data. Therefore, the aim of this study was to analyze our experience and to identify predictive factors for DGE by applying the ISGPS classification at a high-volume hospital. METHODS: From October 2002 to December 2007, 129 consecutive patients underwent PD at the Department of Surgery, Yonsei University Medical Center. The severity of DGE was determined according to the ISGPS classification, and risk factors were evaluated retrospectively. RESULTS: The overall incidence of DGE was 33.3%, with 16 (12.4%) patients having grade A, 14 (10.9%) grade B, and 13 (10.1%) grade C. Clinical outcomes worsened progressively as clinical relevant DGE increased. In multivariate analysis, clinically relevant pancreatic fistula (grade B/C) and patients with benign pathology were identified as independent factors for DGE. CONCLUSION: Pancreatic leakage is a serious complication after PD and is also associated with DGE. The ISGPS classification is a clear and useful tool to assess clinical outcomes.
Authors:
Joon Seong Park; Ho Kyoung Hwang; Jae Keun Kim; Sin Il Cho; Dong-Sup Yoon; Woo Jung Lee; Hoon Sang Chi
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Publication Detail:
Type:  Journal Article; Validation Studies     Date:  2009-07-18
Journal Detail:
Title:  Surgery     Volume:  146     ISSN:  1532-7361     ISO Abbreviation:  Surgery     Publication Date:  2009 Nov 
Date Detail:
Created Date:  2009-10-19     Completed Date:  2009-11-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0417347     Medline TA:  Surgery     Country:  United States    
Other Details:
Languages:  eng     Pagination:  882-7     Citation Subset:  AIM; IM    
Affiliation:
Department of Surgery, Yonsei University College of Medicine, Seoul, Korea.
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MeSH Terms
Descriptor/Qualifier:
Aged
Female
Gastric Emptying*
Hospitals, University
Humans
Incidence
Male
Middle Aged
Multivariate Analysis
Pancreaticoduodenectomy / adverse effects*
Postoperative Complications
Retrospective Studies
Risk Factors
Stomach Diseases / classification,  etiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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