| Clinical utility of three-dimensional integrated 18F-fluorodeoxyglucose positron-emission tomography/computed tomography virtual mediastinoscopy. | |
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MedLine Citation:
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PMID: 20299443 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The objectives of this study were to devise a new image processing technique to reconstruct dynamic three-dimensional (3D) virtual mediastinoscopic images on the basis of positron-emission tomography/computed tomography (PET/CT) datasets, and to examine the clinical utility of this technique for preoperative simulation of and intraoperative guidance during mediastinoscopic nodal biopsy. Of 54 patients with suspected or proven lung cancer (LC) who underwent mediastinoscopy between January 2005 and December 2007, 37 also underwent preoperative PET/CT. Of these 37 patients, we tested our image processing protocol in 15 consecutive patients with significant mediastinal uptake of fluorodeoxyglucose (FDG). We reconstructed 3D virtual mediastinoscopy movies in two mutually complementary demonstration modes--the tracheobronchial- and vessel-modes--with accurate representation of actual mediastinoscopic procedures. The benefit of these virtual imaging was evaluated with regard to their utility in mediastinoscopic nodal biopsy. Our new technique enabled better understanding of the spatial interrelationship between FDG-avid nodes and mediastinal structures. It facilitated more accurate and safer nodal biopsy under virtual guidance. In conclusion, we showed the feasibility of our virtual mediastinoscopic technique, which may improve the procedural safety and diagnostic accuracy of mediastinoscopic nodal biopsy and nodal staging in LC. |
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Authors:
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Hideki Itano; Yutaka Hirokawa; Koumei Takauchi |
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Publication Detail:
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Type: Evaluation Studies; Journal Article Date: 2010-03-18 |
Journal Detail:
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Title: Interactive cardiovascular and thoracic surgery Volume: 10 ISSN: 1569-9285 ISO Abbreviation: Interact Cardiovasc Thorac Surg Publication Date: 2010 Jun |
Date Detail:
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Created Date: 2010-05-18 Completed Date: 2010-08-24 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101158399 Medline TA: Interact Cardiovasc Thorac Surg Country: England |
Other Details:
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Languages: eng Pagination: 981-5 Citation Subset: IM |
Affiliation:
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Department of Thoracic Surgery, Kure Kyosai Hospital, Kure, Japan. itano_h@yahoo.co.jp |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Aged, 80 and over Biopsy Feasibility Studies Female Fluorodeoxyglucose F18 / diagnostic use* Humans Image Interpretation, Computer-Assisted* Imaging, Three-Dimensional* Lung Neoplasms / diagnosis*, radiography, radionuclide imaging, surgery Lymph Nodes* / radiography, radionuclide imaging Male Mediastinoscopy* Middle Aged Neoplasm Staging Positron-Emission Tomography* Predictive Value of Tests Radiopharmaceuticals / diagnostic use* Tomography, X-Ray Computed* |
| Chemical | |
Reg. No./Substance:
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0/Radiopharmaceuticals; 63503-12-8/Fluorodeoxyglucose F18 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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