Document Detail

Clinical utility, safety and tolerability of capsule endoscopy in urban Southeast Asian population.
MedLine Citation:
PMID:  14562399     Owner:  NLM     Status:  MEDLINE    
AIM: Capsule endoscopy has demonstrated its clinical utility in the evaluation of small bowel pathology in several Western studies. In this prospective study, we aimed to determine the clinical utility, safety and tolerability of capsule endoscopy in the evaluation of suspected small bowel disease in an urban Southeast Asian population. METHODS: We used the given (M2A) capsule endoscopy system in 16 consecutive patients with suspected small bowel pathology. In 9 patients the indication was obscure gastrointestinal bleeding, while in 6 patients it was to determine the extent of small bowel involvement in Crohn's disease. One patient underwent capsule endoscopy for evaluation of chronic abdominal pain. Patient's tolerability to the procedure was evaluated by standardized questionnaires and all patients were reviewed at one week to ensure that the capsule had been excreted without any adverse events. RESULTS: Abnormal findings were present in 8 patients (50%). The cause of obscure gastrointestinal bleeding was determined in 5 out of 9 patients. Findings included 2 cases of angiodysplasia, 2 cases of jejunal ulcers and 1 case of both angiodysplasia and jejunal ulcer. One patient had small bowel erosions and foci of erythema of doubtful significance. Ileal lesions were diagnosed in 2 out of 6 patients with Crohn's disease. Capsule endoscopy was well tolerated by all patients. One patient with Crohn's disease had a complication of capsule retention due to terminal ileum stricture. The capsule eventually passed out spontaneously after 1 month. CONCLUSION: Our study, which represented the first Asian series, further confirms the diagnostic utility, safety and tolerability of wireless capsule endoscopy.
Tiing-Leong Ang; Kwong-Ming Fock; Tay-Meng Ng; Eng-Kiong Teo; Yi-Lyn Tan
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Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  World journal of gastroenterology : WJG     Volume:  9     ISSN:  1007-9327     ISO Abbreviation:  World J. Gastroenterol.     Publication Date:  2003 Oct 
Date Detail:
Created Date:  2003-10-16     Completed Date:  2003-12-03     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  100883448     Medline TA:  World J Gastroenterol     Country:  China    
Other Details:
Languages:  eng     Pagination:  2313-6     Citation Subset:  IM    
Division of Gastroenterology, Department of Medicine, Changi General Hospital, Singapore.
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MeSH Terms
Endoscopy, Digestive System / adverse effects,  methods*
Intestinal Diseases / diagnosis*
Intestine, Small
Middle Aged
Patient Satisfaction
Prospective Studies

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