| Clinical usefulness of 111In-oxine-labeled autologous lymphocytes in kidney-graft rejection. | |
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MedLine Citation:
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PMID: 3924619 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A method of lymphocyte labeling with 111In-oxine was applied for the diagnosis of acute kidney-graft rejection. After the injection of labeled lymphocytes, scintigrams of the graft area, contralateral iliac fossa, and spleen were obtained. Indexes of activity were calculated. No patient without rejection (n = 3) showed lymphocyte graft deposition. Twenty-two patients with acute graft rejection and two patients with on abdominal-wall abscess over the graft area showed lymphocyte graft trapping. When acute graft rejection was present, index i (graft/contralateral iliac fossa) increased, and index c (spleen/graft) decreased. The improvement after the rejection crisis occurred parallel to the decrease in index i. Index c remained unchange regardless of rejection evolution. In summary, 111In-oxine-labeled lymphocytes may be used for the diagnosis of acute kidney-graft rejection and for evolving control. |
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Authors:
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J Martin-Comin; M Roca; J M Griñó; C Paradell; A Caralps |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: European journal of nuclear medicine Volume: 10 ISSN: 0340-6997 ISO Abbreviation: Eur J Nucl Med Publication Date: 1985 |
Date Detail:
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Created Date: 1985-08-09 Completed Date: 1985-08-09 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7606882 Medline TA: Eur J Nucl Med Country: GERMANY, WEST |
Other Details:
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Languages: eng Pagination: 308-12 Citation Subset: IM |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Graft Rejection* Humans Hydroxyquinolines / diagnostic use* Indium / diagnostic use* Kidney / radionuclide imaging Kidney Transplantation* Lymphocytes* Organometallic Compounds* Oxyquinoline / analogs & derivatives, diagnostic use* |
| Chemical | |
Reg. No./Substance:
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0/Hydroxyquinolines; 0/Organometallic Compounds; 14514-42-2/indium oxine; 148-24-3/Oxyquinoline; 7440-74-6/Indium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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