Document Detail

Clinical use of the perifollicular vascularity assessment in IVF cycles: a pilot study.
MedLine Citation:
PMID:  16373407     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: In Italy, a recent law has imposed a ban on the fertilization of more than three oocytes at one time, and all resulting embryos produced must be transferred simultaneously. The aim of the present controlled study was to assess the clinical feasibility and efficacy of the perifollicular vascularity assessment for oocyte selection in IVF cycles. METHODS: Fifty-four young primary infertile non-obese women (27 cases and 27 age- and BMI-matched controls) underwent IVF cycles. The choice of the oocytes to fertilize was performed according to perifollicular vascularization in the experimental group, whereas in the control group, the standard morphologic criteria alone were used. The dose of gonadotrophins used, the dominant follicles obtained, the duration of the ovarian stimulation, the number of oocytes retrieved, the number/quality of oocytes fertilized and of cleaved embryos, cycle cancellation, implantation, clinical pregnancy, ongoing pregnancy, multiple pregnancies and ovarian hyperstimulation syndrome rates were assessed in each group. RESULTS: The assessment of perifollicular vascularity was feasible in 88.9% of cases. No difference between groups was detected in any parameter evaluated. CONCLUSION: Power Doppler assessment of perifollicular vascularity seems to have no clinical utility for oocyte selection in IVF cycles for young infertile women.
Stefano Palomba; Tiziana Russo; Angela Falbo; Francesco Orio; Francesco Manguso; Ermal Nelaj; Achille Tolino; Annamaria Colao; Brian Dale; Fulvio Zullo
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Publication Detail:
Type:  Clinical Trial; Journal Article     Date:  2005-12-22
Journal Detail:
Title:  Human reproduction (Oxford, England)     Volume:  21     ISSN:  0268-1161     ISO Abbreviation:  Hum. Reprod.     Publication Date:  2006 Apr 
Date Detail:
Created Date:  2006-03-22     Completed Date:  2006-06-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8701199     Medline TA:  Hum Reprod     Country:  England    
Other Details:
Languages:  eng     Pagination:  1055-61     Citation Subset:  IM    
Department of Obstetrics & Gynecology, University Magna Graecia of Catanzaro, Catanzaro, Italy.
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MeSH Terms
Embryo Transfer
Fertilization in Vitro*
Infertility, Female / therapy
Oocytes / physiology
Ovarian Follicle / blood supply*,  cytology,  ultrasonography
Pilot Projects
Pregnancy Rate
Ultrasonography, Doppler

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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