| Clinical use of Heliox in asthma and COPD. | |
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MedLine Citation:
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PMID: 18018756 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Heliox is a low density gas mixture of helium and oxygen commonly used in deep diving (> 6 ATM). This mixture has been also used for clinical purposes, particularly in the critical care setting. Due to of its physical proprieties, Heliox breathing reduces air flow resistances within the bronchial tree; in patients with obstructive lung diseases Heliox may also reduce the work of breathing and improve pulmonary gas exchange efficiency. Beneficial effects have been documented in severe asthma attacks and in patients with chronic obstructive pulmonary disease. A reduction in WOB during mechanical ventilation and an increase in exercise endurance capacity have also been described in COPD. Heliox has been also used in the treatment of upper airways obstruction, bronchiolitis and bronchopulmonary dysplasia. Despite the encouraging results, Heliox use in routine practice remains controversial because of technical implications and high costs. |
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Authors:
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G Valli; P Paoletti; D Savi; D Martolini; P Palange |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace / Fondazione clinica del lavoro, IRCCS [and] Istituto di clinica tisiologica e malattie apparato respiratorio, Università di Napoli, Secondo ateneo Volume: 67 ISSN: 1122-0643 ISO Abbreviation: Monaldi Arch Chest Dis Publication Date: 2007 Sep |
Date Detail:
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Created Date: 2007-11-16 Completed Date: 2008-02-05 Revised Date: 2008-06-02 |
Medline Journal Info:
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Nlm Unique ID: 9307314 Medline TA: Monaldi Arch Chest Dis Country: Italy |
Other Details:
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Languages: eng Pagination: 159-64 Citation Subset: IM |
Affiliation:
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Dipartimento Medicina Clinica, Università "La Sapienza", Roma, Italy. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Airway Resistance
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drug effects Asthma / physiopathology, therapy* Helium / pharmacology, therapeutic use* Humans Oxygen / pharmacology, therapeutic use* Oxygen Inhalation Therapy / methods* Pulmonary Disease, Chronic Obstructive / physiopathology, therapy* |
| Chemical | |
Reg. No./Substance:
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58933-55-4/heliox; 7440-59-7/Helium; 7782-44-7/Oxygen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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