| Clinical trials in the surgical management of congestive heart failure: surgical ventricular restoration and autologous skeletal myoblast and stem cell cardiomyoplasty. | |
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MedLine Citation:
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PMID: 14988626 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Despite continued advances in medical and surgical approaches for patients with ischemic cardiomyopathy, congestive heart failure (CHF) remains a growing cause of morbidity and mortality. Historically, surgical options for end-stage CHF have been limited. However, there are several surgical therapies now under clinical investigation that appear promising in the effort to reverse or restore the remodeled left ventricle. This review will focus on early but current clinical studies examining surgical ventricular restoration and autologous skeletal myoblast and stem cell transplantation. Although these emerging therapeutic options remain in the early stages of study and development, they hold promise in providing options to those patients with end-stage CHF. |
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Authors:
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Patrick I McConnell; Robert E Michler |
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Publication Detail:
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Type: Comparative Study; Journal Article; Review |
Journal Detail:
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Title: Cardiology Volume: 101 ISSN: 0008-6312 ISO Abbreviation: Cardiology Publication Date: 2004 |
Date Detail:
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Created Date: 2004-02-27 Completed Date: 2004-07-19 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 1266406 Medline TA: Cardiology Country: Switzerland |
Other Details:
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Languages: eng Pagination: 48-60 Citation Subset: IM |
Copyright Information:
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Copyright 2004 S. Karger AG, Basel |
Affiliation:
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The Ohio State University Medical Center, Columbus, Ohio 43210, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Cardiomyoplasty / methods* Clinical Trials as Topic Heart Failure / mortality, surgery* Heart Ventricles / surgery* Humans Myoblasts / transplantation* Myocardial Infarction / complications, mortality, surgery Myocardial Ischemia / mortality, surgery* Outcome and Process Assessment (Health Care) Postoperative Complications / surgery Stem Cell Transplantation / methods* Survival Analysis Ventricular Remodeling / physiology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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