| Clinical trials in healthy volunteers with the new purified chick embryo cell rabies vaccine for man. | |
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MedLine Citation:
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PMID: 12055789 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Behringwerke has developed the new, safe and economical purified chick embryo cell (PCEC) rabies vaccine. Due to the purification by zonal centrifugation the compatibility of this vaccine is excellent. Among 933 vaccinations in 219 healthy volunteers the only side-effect was mild pain at the injection-site in 17 vaccinations (1.7 per cent). The sero-conversion of PCEC rabies vaccine was 100 per cent in the tested healthy volunteers. The kinetics of antibody induction after PCEC rabies vaccine is comparable to antibody induction after HDC rabies vaccine. PCEC rabies vaccine induces cellular immunity as measured in lymphocyte transformation test, but no interferon activity. |
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Authors:
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U Bijok; R Barth; H Gruschkau; I Vodopija; S Smerdel; H Kukla; R Geursen |
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Publication Detail:
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Type: Clinical Trial; Journal Article |
Journal Detail:
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Title: The Journal of communicable diseases Volume: 16 ISSN: 0019-5138 ISO Abbreviation: J Commun Dis Publication Date: 1984 Mar |
Date Detail:
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Created Date: 2002-06-11 Completed Date: 2002-08-02 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0261652 Medline TA: J Commun Dis Country: India |
Other Details:
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Languages: eng Pagination: 61-9 Citation Subset: IM |
Affiliation:
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Behring Werke AG, Marburg, West Germany. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Antibodies, Viral / immunology* Female Health Humans Immunization, Secondary Interferons / immunology Lymphocyte Activation Male Middle Aged Rabies / immunology*, prevention & control Rabies Vaccines / adverse effects*, immunology* Rabies virus / immunology |
| Chemical | |
Reg. No./Substance:
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0/Antibodies, Viral; 0/Rabies Vaccines; 9008-11-1/Interferons |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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