Document Detail

Clinical trials in elderly patients.
MedLine Citation:
PMID:  17117717     Owner:  NLM     Status:  MEDLINE    
The increasing size of the elderly population means that both the relative and absolute numbers of prescriptions for elderly patients are increasing. Depending on the age group, between 60% and 80% of elderly people are taking medication, and between 20% and 30% are taking at least three drugs. Prescribing for elderly patients as opposed to younger patients is thus ever more important. This has inevitably meant that the drug development process must increasingly recognise the importance of identifying and developing therapeutic targets relevant to older patients. Clearly, the scientific ethical and regulatory principles that determine conduct of clinical trials in younger individuals apply equally to older people. In addition, the development of drugs to be used in older patients requires an awareness of a number of physiological, pathophysiological and sociological considerations.
S H D Jackson
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Ernst Schering Research Foundation workshop     Volume:  -     ISSN:  0947-6075     ISO Abbreviation:  Ernst Schering Res. Found. Workshop     Publication Date:  2007  
Date Detail:
Created Date:  2006-11-22     Completed Date:  2006-12-12     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  9422786     Medline TA:  Ernst Schering Res Found Workshop     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  101-9     Citation Subset:  IM    
Department of Clinical Gerontology, King's College Hospital, London, UK.
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MeSH Terms
Adipose Tissue
Clinical Trials as Topic / methods*
Drug Prescriptions
Glomerular Filtration Rate
Liver / metabolism,  pathology*
Patient Selection
Research Design

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