Document Detail


Clinical trials of coronary revascularization for chronic stable angina: medical treatment versus coronary revascularization.
MedLine Citation:
PMID:  11139091     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
For patients with chronic stable angina, several randomized trials have been performed comparing medical management with surgery, medical management with angioplasty, and angioplasty with surgery. Data from the medical versus revascularization trials (either surgery or angioplasty) support the following contentions: For patients with multivessel disease, particularly involving the proximal left anterior descending coronary artery, survival is superior to surgical treatment. Symptom relief with either type of revascularization is superior to medical management. The subsequent rate of myocardial infarction is not affected by the initial treatment strategy, whether medical, angioplasty, or surgery. In individual patients the potential benefits of any revascularization strategy must be weighed against its initial risks. Further study is needed, particularly with multifaceted pharmacologic therapy and with updated angioplasty techniques, to evaluate relative survival benefits in these patients. The studies supporting these conclusions are highlighted in this paper.
Authors:
A F Parisi
Publication Detail:
Type:  Comparative Study; Journal Article; Review    
Journal Detail:
Title:  Current opinion in cardiology     Volume:  15     ISSN:  0268-4705     ISO Abbreviation:  Curr. Opin. Cardiol.     Publication Date:  2000 Jul 
Date Detail:
Created Date:  2001-01-02     Completed Date:  2001-03-29     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8608087     Medline TA:  Curr Opin Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  275-80     Citation Subset:  IM    
Affiliation:
The Miriam Hospital, Division of Cardiology, Providence, Rhode Island 02906, USA. aparisi@lifespan.org
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MeSH Terms
Descriptor/Qualifier:
Angina Pectoris / drug therapy,  mortality,  surgery*
Angioplasty, Transluminal, Percutaneous Coronary
Chronic Disease
Coronary Artery Bypass
Disease-Free Survival
Female
Humans
Male
Middle Aged
Myocardial Infarction / diagnosis
Myocardial Revascularization*
Randomized Controlled Trials as Topic

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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