| Clinical trials of coronary revascularization: coronary angioplasty vs. coronary bypass grafting. | |
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MedLine Citation:
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PMID: 11139092 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In the absence of diabetes mellitus, rates of survival and of survival free of myocardial infarction (MI) are almost identical among patients with multivessel disease assigned to percutaneous transluminal coronary angioplasty (PTCA) versus those assigned to coronary artery bypass grafting (CABG) after 6.5 to 8 year follow-up period. Additional revascularization occurs 2.5 to 4.5 times more frequently in PTCA-treated than in CABG-treated patients and prevalence of angina is no longer statistically different between the two treatment groups. The excess health care costs of bypass surgery, which are important early after revascularization, almost disappear 5 to 8 years later. In patients with single vessel disease, survival free of MI is also comparable in both treatment groups at 5 years. Additional revasculariztion occurs two to four times more often in PTCA-treated than in CABG-treated patients and prevalence of angina does not differ between the two treatment groups. Thus, in nondiabetic patients with multivessel disease, the choice of a revascularization strategy rests on the patient's and treating physician's preference between the invasive nature of bypass surgery and the risk of recurrent procedures. In patients with single vessel disease, these long-term data suggest that bypass surgery is at least as safe and effective as coronary angioplasty and therefore may be a treatment option in selected cases. |
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Authors:
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M G Bourassa |
Publication Detail:
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Type: Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial; Review |
Journal Detail:
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Title: Current opinion in cardiology Volume: 15 ISSN: 0268-4705 ISO Abbreviation: Curr. Opin. Cardiol. Publication Date: 2000 Jul |
Date Detail:
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Created Date: 2001-01-02 Completed Date: 2001-03-29 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8608087 Medline TA: Curr Opin Cardiol Country: United States |
Other Details:
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Languages: eng Pagination: 281-6 Citation Subset: IM |
Affiliation:
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Research Center, Montreal Heart Institute, Quebec, Canada. bourassa@icm.umontreal.ca |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Angina Pectoris
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diagnosis Angioplasty, Transluminal, Percutaneous Coronary* Coronary Artery Bypass* Coronary Disease / economics, mortality, surgery* Cost of Illness Disease-Free Survival Humans Myocardial Infarction / diagnosis Randomized Controlled Trials as Topic Stents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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