Document Detail

Clinical trial with lorazepam in pre-operative anxiety.
MedLine Citation:
PMID:  22214     Owner:  NLM     Status:  MEDLINE    
An important part of the pre-operative preparation of a patient consists in the treatment of his anxiety. One hundred eighty-two patients (varying in age from 17 to 80 years) were sedated for surgery with lorazepam. The evening before intervention, each patient received 1 tablet of lorazepam (2.5 mg) and on the day of operation (90 minutes before induction of the anesthesia), each patient received an I.M. injection of lorazepam and atropine, the dosage being adjusted to body weight. The prior administration of lorazepam usually gives very good results with only slight risk of side-effects and without unhappy recollections of the pre- and post-operative periods. Most of the patients were very calm, being well rested, conscious and capable of conversation. In our experience the sedation of anxious patients with lorazepam would seem to be a very good and safe procedure.
L Baute
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta anaesthesiologica Belgica     Volume:  28     ISSN:  0001-5164     ISO Abbreviation:  Acta Anaesthesiol Belg     Publication Date:  1977  
Date Detail:
Created Date:  1978-01-27     Completed Date:  1978-01-27     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0421022     Medline TA:  Acta Anaesthesiol Belg     Country:  BELGIUM    
Other Details:
Languages:  eng     Pagination:  123-31     Citation Subset:  IM    
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MeSH Terms
Anti-Anxiety Agents / pharmacology*
Anxiety / drug therapy*
Lorazepam / adverse effects,  pharmacology*
Memory / drug effects
Middle Aged
Sleep / drug effects
Reg. No./Substance:
0/Anti-Anxiety Agents; 846-49-1/Lorazepam

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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