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Clinical trial: a randomized study comparing the durability of silicone and latex percutaneous endoscopic gastrostomy tubes.
MedLine Citation:
PMID:  21429018     Owner:  NLM     Status:  In-Data-Review    
Background:  The use of percutaneous endoscopic gastrostomy (PEG) for nutrition support is increasing worldwide, but few studies have evaluated the durability of and complications related to the different materials used to manufacture gastrostomy tubes. Latex PEG tubes are widely used in our clinical setting, but no studies have compared their durability with silicone PEG tubes. The aim of the present study was to compare the durability of latex tubes with the durability of silicone tubes. Patients and Methods:  A randomized clinical trial was conducted in patients with head and neck cancer with indications for PEG. Sixty patients were randomized to receive either latex or silicone PEG tubes and followed up for 90 days. The analyzed outcomes were duration, peristomal infection, granulated tissue formation, and leakage around the tube. Results:  The durability of silicone PEG tubes was significantly greater than the durability of latex PEG tubes. The survival curves showed that silicone PEG tubes lasted twice as long (hazard ratio = 2.0, 95% confidence interval = 1.1-3.7, P = 0.01). No differences were found with regard to rate of peristomal infection, granulated tissue formation, or leakage. Conclusion:  Silicone PEG tubes are associated with a reduced need for replacement (attributable to higher durability) compared with latex PEG tubes.
Paulo Campoli; Daniela Cardoso; Marilia Turchi; Orlando Mota
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Publication Detail:
Type:  Journal Article     Date:  2010-12-07
Journal Detail:
Title:  Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society     Volume:  23     ISSN:  1443-1661     ISO Abbreviation:  Dig Endosc     Publication Date:  2011 Apr 
Date Detail:
Created Date:  2011-03-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9101419     Medline TA:  Dig Endosc     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  135-9     Citation Subset:  IM    
Copyright Information:
© 2010 The Authors. Digestive Endoscopy © 2010 Japan Gastroenterological Endoscopy Society.
Department of Gastrointestinal Endoscopy Gastrointestinal Surgery, Araujo Jorge Hospital Institute of Tropical Pathology and Public Health, Federal University of Goias, Goias, Brazil.
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