Document Detail


Clinical trial of peptichemio in solid tumors of childhood.
MedLine Citation:
PMID:  356966     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Peptichemio (PTC) was utilized in various advanced and disseminated tumors in children. With the schedule that was used, toxicity was mild. Immediate side effects included anaphylactoid reactions which required close supervision of the patient during infusion of the drug. PTC proved efficacious in advanced neuroblastoma. In patients with bone metastases, PTC has a prompt analgesic effect which seems to occur independently of any antitumor action.
Authors:
J Otten; R Maurus
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Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  Cancer treatment reports     Volume:  62     ISSN:  0361-5960     ISO Abbreviation:  Cancer Treat Rep     Publication Date:  1978 Jul 
Date Detail:
Created Date:  1978-11-27     Completed Date:  1978-11-27     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7607107     Medline TA:  Cancer Treat Rep     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1015-9     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Child
Child, Preschool
Clinical Trials as Topic
Drug Evaluation
Drug Hypersensitivity / etiology
Female
Humans
Infant
Leukopenia / chemically induced
Male
Neoplasm Metastasis
Neoplasms / drug therapy*
Neuroblastoma / drug therapy
Nitrogen Mustard Compounds / therapeutic use*
Peptichemio / adverse effects,  pharmacology,  therapeutic use*
Thrombocytopenia / chemically induced
Chemical
Reg. No./Substance:
0/Nitrogen Mustard Compounds; 9076-25-9/Peptichemio

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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