Document Detail


Clinical and topographic magnetic resonance imaging characteristics of suspected thalamic infarcts in 16 dogs.
MedLine Citation:
PMID:  20456988     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Sixteen dogs with acute-onset, non-progressive signs of brain dysfunction and magnetic resonance imaging (MRI) characteristics compatible with thalamic infarction are described. Topographically the MRI lesions could be grouped in three thalamic regions, namely, paramedian (8/16), extensive dorsal (5/16) and ventrolateral (3/16). Paramedian lesions resulted in signs typical of vestibular dysfunction. Extensive dorsal lesions were associated with vestibular ataxia, circling and contralateral menace response deficits. Ventrolateral lesions resulted in circling and contralateral proprioceptive deficits. In several dogs, regions other than the thalamus were also affected: four extended into the midbrain; six extended to the internal capsule, and two dogs had a second lesion in the cerebellum. Three clinical syndromes were identified in association with thalamic infarction. These signs varied somewhat, most likely because lesions were not confined to specific nuclear boundaries and involved different combinations of thalamic nuclei.
Authors:
Rita Gonçalves; Inés Carrera; Laurent Garosi; Peter M Smith; J Fraser McConnell; Jacques Penderis
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Publication Detail:
Type:  Journal Article     Date:  2010-04-24
Journal Detail:
Title:  Veterinary journal (London, England : 1997)     Volume:  188     ISSN:  1532-2971     ISO Abbreviation:  Vet. J.     Publication Date:  2011 Apr 
Date Detail:
Created Date:  2011-03-18     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9706281     Medline TA:  Vet J     Country:  England    
Other Details:
Languages:  eng     Pagination:  39-43     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 Elsevier Ltd. All rights reserved.
Affiliation:
Department of Veterinary Science, Small Animal Teaching Hospital, University of Liverpool, Leahurst, Chester High Road, Neston CH64 7TE, UK.
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