Document Detail


Clinical therapeutics in pregnancy.
MedLine Citation:
PMID:  21785566     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Most drugs are not tested for use during pregnancy, consequently, labeling, which may include information about fetal safety, includes nothing about dosing, efficacy, or maternal safety. Yet these are concerns of health care providers considering treatment of disease during pregnancy. Therefore, the practitioner treats the pregnant woman with the same dose recommended for use in adults (typically men) or may decide not to treat the disease at all. However, is the choice of not treating a woman during pregnancy better than dealing with the challenges which accompany treatment? This paper, which summarizes metabolic and physiologic changes induced by pregnancy, illustrates that standard adult dosing is likely to be incorrect during pregnancy.
Authors:
Maisa N Feghali; Donald R Mattison
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Publication Detail:
Type:  Journal Article     Date:  2011-07-06
Journal Detail:
Title:  Journal of biomedicine & biotechnology     Volume:  2011     ISSN:  1110-7251     ISO Abbreviation:  J. Biomed. Biotechnol.     Publication Date:  2011  
Date Detail:
Created Date:  2011-07-25     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101135740     Medline TA:  J Biomed Biotechnol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  783528     Citation Subset:  -    
Affiliation:
Department of Obstetrics and Gynecology, Washington Hospital Center, Washington, DC 20010, USA.
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