| Clinical therapeutics in pregnancy. | |
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MedLine Citation:
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PMID: 21785566 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Most drugs are not tested for use during pregnancy, consequently, labeling, which may include information about fetal safety, includes nothing about dosing, efficacy, or maternal safety. Yet these are concerns of health care providers considering treatment of disease during pregnancy. Therefore, the practitioner treats the pregnant woman with the same dose recommended for use in adults (typically men) or may decide not to treat the disease at all. However, is the choice of not treating a woman during pregnancy better than dealing with the challenges which accompany treatment? This paper, which summarizes metabolic and physiologic changes induced by pregnancy, illustrates that standard adult dosing is likely to be incorrect during pregnancy. |
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Authors:
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Maisa N Feghali; Donald R Mattison |
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Publication Detail:
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Type: Journal Article Date: 2011-07-06 |
Journal Detail:
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Title: Journal of biomedicine & biotechnology Volume: 2011 ISSN: 1110-7251 ISO Abbreviation: J. Biomed. Biotechnol. Publication Date: 2011 |
Date Detail:
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Created Date: 2011-07-25 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101135740 Medline TA: J Biomed Biotechnol Country: United States |
Other Details:
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Languages: eng Pagination: 783528 Citation Subset: - |
Affiliation:
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Department of Obstetrics and Gynecology, Washington Hospital Center, Washington, DC 20010, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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