| Clinical and therapeutic characterization of a Portuguese sample of patients with schizophrenia. | |
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MedLine Citation:
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PMID: 21560074 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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INTRODUCTION: The development of Mental Health policies for psychiatric disorders should be driven by a correct knowledge of the socio-demographic, clinical and therapeutic realities of the disease. There is paucity of detailed studies in the Portuguese population that does not allow a direct comparation with other European countries. The objective of the present study is to characterize the sociodemograhic and clinical characteristics of schizophrenia patients in Portugal and the therapeutic patterns. METHODS: This multicentric, cross sectional, non interventional study was designed to describe the demographic and clinical data of patients with schizophrenia (n=474), and also the demographic and professional characteristics of their treating psychiatrists. RESULTS: The most frequent diagnosis found was paranoid schizophrenia (54%), with comorbid psychiatric conditions in 39,7% and somatic diseases in 28.4% of the patients. About half the patients were on second generation antipsychotics (SGS) as principal therapy, although haloperidol has been the most frequent drug prescribed as so (35.9 %). 59.51 % of the patients were on antipsychotic monotherapy, and 45% on a depot formulation. Antipsychotic dose vary widely, and they are quite often prescribed on off label doses. DISCUSSION: Our sample is similar to others found in naturalistic studies, however slightly different from clinical trials. In general, patients with schizophrenia tend to be treated with SGA, although have a higher chance to be on a long-term formulation and to be on polytherapy than in other studies. Somatic diseases are maybe under diagnosed and are undertreated. |
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Authors:
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Frederico Simões do Couto; Cristina Queiroz; Teresa Barbosa; Luis Ferreira; Horácio Firmino; Miguel Viseu; Luisa Ramos; Jose Romero; Maria Luisa Figueira; |
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Publication Detail:
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Type: Journal Article; Multicenter Study Date: 2011-05-01 |
Journal Detail:
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Title: Actas españolas de psiquiatría Volume: 39 ISSN: 1578-2735 ISO Abbreviation: Actas Esp Psiquiatr Publication Date: 2011 May-Jun |
Date Detail:
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Created Date: 2011-05-11 Completed Date: 2011-08-03 Revised Date: 2011-11-03 |
Medline Journal Info:
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Nlm Unique ID: 100886502 Medline TA: Actas Esp Psiquiatr Country: Spain |
Other Details:
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Languages: eng Pagination: 147-54 Citation Subset: IM |
Affiliation:
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Clínica Universitária de Psiquiatria Faculdade de Medicina de Lisboa Lisboa, Portugal Instituto de Farmacologia e Neurociencias Instituto de Medicina Molecular Lisboa, Portugal. fcouto@fm.ul.pt |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Child Cross-Sectional Studies Female Humans Male Middle Aged Portugal Schizophrenia / diagnosis*, therapy* Young Adult |
| Investigator | |
Investigator/Affiliation:
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Eurico Allen Revez / ; Teresa Babo / ; Teresa Barbosa / ; Teresa Cabral / ; Sílvia Castro / ; Rui Correia / ; Isabel Cruz / ; António José Daskalos / ; Maria Luísa Figueira / ; Zélia Figueiredo / ; José Manuel Jara / ; Luís Ferreira / ; António Marieiro / ; Amélia Martins / ; João Marques Teixeira / ; Vitor Oliveira / ; António Palha / ; Carlos Paz Ferreira / ; António Pissarra da Costa / ; María Clara Rosa / ; José Salgado / ; Érico da Silveira Alves / ; Jorge Tudela / ; María José Varanda / ; Adriano Vaz Serra / ; Miguel Viseu / |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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